652-67-5Relevant articles and documents
Heterogeneous cyclization of sorbitol to isosorbide catalyzed by a novel basic porous polymer-supported ionic liquid
Wang, Yao-Feng,Xu, Bao-Hua,Du, Yi-Ran,Zhang, Suo-Jiang
, p. 59 - 66 (2018)
In this study, heterogeneous cyclization of sorbitol to isosorbide under basic condition was realized for the first time with a novel porous polymer-supported ionic liquid as catalyst. These polymer-supported ILs were synthesized through the suspension polymerization of 4-vinylbenzyl chloride and divinylbenzene, followed by a quaternization reaction. As compared to those of non-porous, the porous polymers had high specific surface area and large number of active sites. Consequently, they exhibited excellent catalytic activity in the cyclization of sorbitol with dimethylcarbonate (DMC) to isosorbide. As a result, a high conversion of sorbitol (99%) was achieved with 83% yield of isosorbide under optimized conditions. Importantly, the catalysts could be easily separated by decantation and reused for five times without obvious loss of catalytic activity.
METHOD FOR PURIFICATION OF ISOSORBIDE
-
Page/Page column 14; 15, (2021/02/26)
The invention relates to a process for purifying a crude isosorbide, in which the crude isosorbide is melted and converted, by cooling, into a crude isosorbide melt suspension consisting of isosorbide crystals and residual melt, the amount by weight of impurities in the isosorbide crystals being less than the amount by weight of impurities in the residual melt, optionally a part of the residual melt is separated off mechanically from the crude isosorbide suspension, further the isosorbide crystals in the melt isosorbide suspension are purified from residual melt by washing with a washing isosorbide melt, the amount by weight of impurities in the washing isosorbide melt being less than the amount by weight of impurities in the residual melt.
Kinetic analyses of intramolecular dehydration of hexitols in high-temperature water
Yamaguchi, Aritomo,Mimura, Naoki,Shirai, Masayuki,Sato, Osamu
, (2019/11/29)
Intramolecular dehydration of the biomass-derived hexitols D-sorbitol, D-mannitol, and galactitol was investigated. These reactions were performed in high-temperature water at 523–573 K without added acid catalyst. The rate constants for the dehydration steps in the reaction networks were determined at various reaction temperatures, and the activation energies and pre-exponential factors were calculated from Arrhenius plots. The yield of each product was estimated as a function of reaction time and temperature using the calculated rate constants and activation energies. The maximum yield of each product from the dehydration reactions was predicted over a range of reaction time and temperature, allowing the selective production of these important platform chemicals.
Direct Amination of Isohexides via Borrowing Hydrogen Methodology: Regio- and Stereoselective Issues
Bahé, Florian,Grand, Lucie,Cartier, Elise,Jacolot, Ma?wenn,Moebs-Sanchez, Sylvie,Portinha, Daniel,Fleury, Etienne,Popowycz, Florence
supporting information, p. 599 - 608 (2020/02/04)
The regio and diastereoselective direct mono or diamination of bio-based isohexides (isosorbide and isomannide) has been developed through borrowing hydrogen (BH) methodology using a cooperative catalysis between an iridium complex and a Br?nsted acid. The access to chiral amino-alcohol (NH2-OH) and diamine (NH2-NH2), interesting optically pure bio-based monomers, was also proposed using BH strategy as a sustainable route for their obtention.
