659-36-9Relevant articles and documents
Direct Deoxyfluorination of Alcohols with KF as the Fluorine Source
Xu, Jun,Peng, Chao,Yao, Bolin,Xu, Hua-Jian,Xie, Qiang
, p. 6471 - 6478 (2022/05/07)
This report describes a method for the deoxyfluorination of alcohols with KF as the fluorine source via in situ generation of highly active CF3SO2F. Diverse functionalities, including halogen, nitro, ketone, ester, alkene, and alkyne, are well tolerated. Mild conditions, a short reaction time, and a wide substrate scope make this method an excellent choice for the construction of C-F bonds.