66131-78-0

Basic information

• Product Name: 2-ACETYLAMINO-5-IODOPYRIDINE
• Synonyms: 2-ACETYLAMINO-5-IODOPYRIDINE;N-(5-IODO-2-PYRIDINYL)ACETAMIDE;N-(5-IODO-PYRIDIN-2-YL)-ACETAMIDE;2-Acetamido-5-iodopyridine;N-(5-Iodopyridine-2-yl)acetamide;2-Acetamido-5-iodopyridine, 2-(Acetylamino)-5-iodopyridine;ACETAMIDE,N-(5-IODO-2-PYRIDINYL)-
• CAS NO: 66131-78-0
• Molecular Formula: C₇H₇IN₂O
• Molecular Weight: 262.05
• Product Categories: pharmacetical;Organohalides;Pyridine
• Mol File: 66131-78-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 156-158°C
• Boiling Point: 405℃
• Flash Point: 199℃
• Appearance: /
• Density: 1.901
• Vapor Pressure: 8.96E-07mmHg at 25°C
• Refractive Index: 1.67
• Storage Temp.: 2-8°C
• Solubility: soluble in Methanol
• PKA: 13.08±0.70(Predicted)
• CAS DataBase Reference: 2-ACETYLAMINO-5-IODOPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ACETYLAMINO-5-IODOPYRIDINE(66131-78-0)
• EPA Substance Registry System: 2-ACETYLAMINO-5-IODOPYRIDINE(66131-78-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 66131-78-0(Hazardous Substances Data)

Usage

General Description

2-ACETYLAMINO-5-IODOPYRIDINE is a chemical compound with the molecular formula C8H8IN3O. It is a pyridine derivative with an acetylamine group and an iodine atom attached to the 5th position of the pyridine ring. 2-ACETYLAMINO-5-IODOPYRIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has been studied for its potential as a building block in the synthesis of various biologically active compounds. 2-ACETYLAMINO-5-IODOPYRIDINE is known for its diverse applications in the pharmaceutical and agricultural industries, and its synthesis and properties are the subject of ongoing research.

InChI:InChI=1/C7H7IN2O/c1-5(11)10-7-3-2-6(8)4-9-7/h2-4H,1H3,(H,9,10,11)

Upstream product

• 504-29-0 2-aminopyridine 
• 20511-12-0 2-amino-5-iodopyridine 
• 108-24-7 acetic anhydride 

Downstream Products

• 177584-46-2 2-(6-Acetylamino-pyridin-3-ylsulfanyl)-benzoic acid 

Relevant articles and documents

COMPOUND HAVING ZNF143 INHIBITORY ACTIVITY AND USE THEREOF

PROBLEM TO BE SOLVED: To provide a compound having a ZNF143 inhibitory activity as well as to provide a ZNF143 inhibitory agent and pharmaceutical composition containing the same. SOLUTION: Provided is a compound represented by formula (I) or a salt thereof as well as a ZNF143 inhibitory agent containing the same and a pharmaceutical composition having the same as an active ingredient. A-B-C-D (I)[A is H, a methyl group, a naphthyl group, a phenyl group or a nitrogen-containing heterocyclic ring; B is as shown below, and C is an amide bond or a heteroaromatic ring containing N and O; D is a substituted/unsubstituted phenyl group or a monocyclic heteroaromatic ring containing N or S; and C and D are both fused heterocyclic ring or the like optionally having a substituent group.]. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2016,JPOandINPIT

SUBSTITUTED PYRIDINE DERIVATIVES AS FABI INHIBITORS

The present invention provides substituted pyridine derivatives of formula (I), which may be therapeutically useful as as anti-bacterial agents, more particulalrly FabI inhibitors. Formula(I) in which R1 to R5 and L have the meanings given in the specification, and pharmaceutically acceptable salts thereof that are useful in the treatment and prevention in diseases or disorder, in particular their use in diseases or disorder where there is an advantage anti-bacterial agents, more particularly FabI inhibitors. The present invention also provides methods for synthesizing and administering the FabI inhibitor compounds. The present invention also provides pharmaceutical formulations comprising at least one of the FabI inhibitor compounds together with a pharmaceutically acceptable carrier, diluent or excipient therefor.

Synthesis and structure elucidation of new cytotoxic azathioxanthones

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