6634-61-3

Basic information

• Product Name: 4-(1,2-diphenylethyl)pyridine
• Synonyms: pyridine, 4-(1,2-diphenylethyl)-
• CAS NO: 6634-61-3
• Molecular Formula: C₁₉H₁₇N
• Molecular Weight: 259.345
• Mol File: 6634-61-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 367.8°C at 760 mmHg
• Flash Point: 156.1°C
• Density: 1.08g/cm³
• Vapor Pressure: 2.83E-05mmHg at 25°C
• Refractive Index: 1.606
• CAS DataBase Reference: 4-(1,2-diphenylethyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1,2-diphenylethyl)pyridine(6634-61-3)
• EPA Substance Registry System: 4-(1,2-diphenylethyl)pyridine(6634-61-3)

Safety Data

• Hazardous Substances Data: 6634-61-3(Hazardous Substances Data)

Usage

General Description

4-(1,2-diphenylethyl)pyridine, also known as DDEP, is a chemical compound that belongs to the family of pyridine derivatives. It is used in organic synthesis as a building block for the production of various pharmaceuticals and agrochemicals. DDEP has been studied for its potential applications in the field of medicinal chemistry, particularly in the development of novel drugs with biological activity. The compound has also been evaluated for its potential use as a precursor for the synthesis of functional materials. Additionally, research has been conducted on the toxicological effects and environmental impact of DDEP, as well as its potential use as a reagent in chemical reactions. Overall, 4-(1,2-diphenylethyl)pyridine is a versatile chemical compound with potential applications in various fields of science and industry.

Upstream product

• 100-48-1 pyridine-4-carbonitrile 
• 94942-89-9 2,3-diphenylpropanoic acid 
• 95745-22-5 4-(1-chloro-1,2-diphenylethyl)pyridine 
• 29958-05-2 4-(2-chloro-1,1-diphenylethyl)pyridine 
• 2116-65-6 4-benzyl pyridine 
• 100-44-7 benzyl chloride 

Relevant articles and documents

Metal-Free Heterogeneous Semiconductor for Visible-Light Photocatalytic Decarboxylation of Carboxylic Acids

A suitable protocol for the photocatalytic decarboxylation of carboxylic acids was developed with metal-free ceramic boron carbon nitrides (BCN). With visible light irradiation, BCN oxidize carboxylic acids to give carbon-centered radicals, which were trapped by hydrogen atom donors or employed in the construction of the carbon-carbon bond. In this system, both (hetero)aromatic and aliphatic acids proceed the decarboxylation smoothly, and C-H, C-D, and C-C bonds are formed in moderate to high yields (35 examples, yield up to 93%). Control experiments support a radical process, and isotopic experiments show that methanol is employed as the hydrogen atom donor. Recycle tests and gram-scale reaction elucidate the practicability of the heterogeneous ceramic BCN photoredox system. It provides an alternative to homogeneous catalysts in the valuable carbon radical intermediates formation. Moreover, the metal-free system is also applicable to late-stage functionalization of anti-inflammatory drugs, such as naproxen and ibuprofen, which enrich the chemical toolbox.