66471-00-9

Basic information

• Product Name: ALLYL N-(2-HYDROXYETHYL)CARBAMATE
• Synonyms: ALLYL N-(2-HYDROXYETHYL)CARBAMATE;N-(ALLYLOXYCARBONYL)ETHANOLAMINE;2-(AllyloxycarbonylaMino)-1-ethanol
• CAS NO: 66471-00-9
• Molecular Formula: C6H11NO3
• Molecular Weight: 145.16
• Mol File: 66471-00-9.mol

Chemical Properties

• Boiling Point: 266.9°C at 760 mmHg
• Flash Point: 109 °C
• Appearance: /
• Density: 1.125 g/mL at 20 °C(lit.)
• Vapor Pressure: 0.00115mmHg at 25°C
• Refractive Index: n20/D 1.471
• PKA: 12.28±0.46(Predicted)
• CAS DataBase Reference: ALLYL N-(2-HYDROXYETHYL)CARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: ALLYL N-(2-HYDROXYETHYL)CARBAMATE(66471-00-9)
• EPA Substance Registry System: ALLYL N-(2-HYDROXYETHYL)CARBAMATE(66471-00-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 66471-00-9(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
ALLYL N-(2-HYDROXYETHYL)CARBAMATE is used as a chemical intermediate for the synthesis of other organic compounds.
Used in Industrial Processes:
ALLYL N-(2-HYDROXYETHYL)CARBAMATE is used as a stabilizer in various industrial processes.
Used in Pharmaceutical Production:
ALLYL N-(2-HYDROXYETHYL)CARBAMATE is used as an intermediate in the production of pharmaceuticals.
Used in Agricultural Chemical Production:
ALLYL N-(2-HYDROXYETHYL)CARBAMATE is used as an intermediate in the production of agricultural chemicals.
Safety:
ALLYL N-(2-HYDROXYETHYL)CARBAMATE is considered to be of low toxicity to humans and the environment, but like all chemicals, should be handled with care and in accordance with proper safety protocols.

InChI:InChI=1/C6H11NO3/c1-2-5-10-6(9)7-3-4-8/h2,8H,1,3-5H2,(H,7,9)

Upstream product

• 141-43-5 ethanolamine 
• 2937-50-0 Allyl chloroformate 
• 75-33-2 2-propanethiol 

Relevant articles and documents

Novel phosphate derivatives as scaffolds for the preparation of synthetic phosphoserine-based peptides using the Fmoc/ t -Bu solid-phase strategy

Synthetic peptides incorporating analogues of phosphoserine are valuable tools for the study of protein kinases and phosphatases. In addition, derivatives of naturally occurring peptides incorporating phosphate groups may have interesting biological properties. Herein we describe a new Fmoc/t-Bu solid-phase peptide synthesis (SPPS) strategy for the convenient generation of phosphoserine-based peptides. A proof-of-concept synthesis that demonstrates the feasibility of this approach is presented. Georg Thieme Verlag Stuttgart - New York.

A mild ligand-free iron-catalyzed liberation of alcohols from allylcarbonates

Different from most carbonates the allyloxy carbonyl protecting group can be cleaved under neutral conditions using metal catalysis. However, most of the catalysts employed to date are based upon precious metals. Herein we present two protocols for the mild Fe-catalyzed liberation of alcohols from allylcarbonates that are characterized by broad functional group tolerance and exclusive chemoselectivity.