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8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one is a white solid chemical compound belonging to the quinoline family. It has a molecular formula of C11H11ClN2O and a molecular weight of 214.67 g/mol.

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  • 676116-21-5 Structure
  • Basic information

    1. Product Name: 8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one
    2. Synonyms: 8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one;8-Chloro-4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one;8-Chloro-4,4-dimethyl-3,4-dihydroquinolin-2(1H)-one
    3. CAS NO:676116-21-5
    4. Molecular Formula: C11H12ClNO
    5. Molecular Weight: 209.67208
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 676116-21-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one(CAS DataBase Reference)
    10. NIST Chemistry Reference: 8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one(676116-21-5)
    11. EPA Substance Registry System: 8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one(676116-21-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 676116-21-5(Hazardous Substances Data)

676116-21-5 Usage

Uses

Used in Pharmaceutical Industry:
8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one is used as an intermediate in the synthesis of various pharmaceuticals for its versatile chemical properties.
Used in Antimalarial Applications:
8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one is used as a key component in the development of antimalarial drugs, contributing to the creation of effective treatments against malaria.
Used in Antitumor Applications:
8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one is utilized in the synthesis of antitumor agents, playing a role in the fight against cancer.
Used in Alzheimer's Disease Treatment Research:
8-Chloro-4,4-diMethyl-1,3-dihydroquinolin-2-one is studied for its potential applications in the treatment of Alzheimer's disease, indicating its possible use in developing therapies for neurodegenerative conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 676116-21-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,7,6,1,1 and 6 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 676116-21:
(8*6)+(7*7)+(6*6)+(5*1)+(4*1)+(3*6)+(2*2)+(1*1)=165
165 % 10 = 5
So 676116-21-5 is a valid CAS Registry Number.

676116-21-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-chloro-4,4-dimethyl-1,3-dihydroquinolin-2-one

1.2 Other means of identification

Product number -
Other names 8-CHLORO-4,4-DIMETHYL-3,4-DIHYDRO-1H-QUINOLIN-2-ONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:676116-21-5 SDS

676116-21-5Downstream Products

676116-21-5Relevant articles and documents

Inhibitors Targeting STAT5 Signaling in Myeloid Leukemias: New Tetrahydroquinoline Derivatives with Improved Antileukemic Potential

Polomski, Marion,Brachet-Botineau, Marie,Juen, Ludovic,Viaud-Massuard, Marie-Claude,Gouilleux, Fabrice,Prié, Gildas

supporting information, p. 1034 - 1046 (2021/01/25)

Signal transducers and activators of transcription 5A and 5B (STAT5A and STAT5B) are two closely related STAT family members that are crucial downstream effectors of tyrosine kinase oncoproteins such as FLT3-ITD in acute myeloid leukemia (AML) and BCR-ABL

HETEROCYCLIC SUBSTITUTED PIPERAZINES FOR THE TREATMENT OF SCHIZOPHRENIA

-

Page 69, (2010/02/06)

This invention relates to compounds of the formula 1 wherein X, Y, Z, A, R', R2, R3, R4, R9, W' and W2 are defined as in the specification, pharmaceutical compositions containing them and their use in the treatment of central nervous system and other diso

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