679431-06-2

Basic information

• Product Name: Benzene, 2-[cis-1-[(4-chlorophenyl)sulfonyl]-4-(iodomethyl)cyclohexyl]-1,4-difluoro-
• CAS NO: 679431-06-2
• Molecular Formula: C19H18ClF2IO2S
• Molecular Weight: 510.771
• Mol File: 679431-06-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzene, 2-[cis-1-[(4-chlorophenyl)sulfonyl]-4-(iodomethyl)cyclohexyl]-1,4-difluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 2-[cis-1-[(4-chlorophenyl)sulfonyl]-4-(iodomethyl)cyclohexyl]-1,4-difluoro-(679431-06-2)
• EPA Substance Registry System: Benzene, 2-[cis-1-[(4-chlorophenyl)sulfonyl]-4-(iodomethyl)cyclohexyl]-1,4-difluoro-(679431-06-2)

Safety Data

• Hazardous Substances Data: 679431-06-2(Hazardous Substances Data)

Upstream product

• 471903-69-2 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid 
• 471903-20-5 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanone 
• 471903-67-0 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid ethyl ester 
• 471903-66-9 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexylidene]-acetic acid ethyl ester 

Downstream Products

• 679431-53-9 2-[4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexylmethylsulfanyl]-pyridine 
• 679431-09-5 Thioacetic acid S-[4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexylmethyl] ester 
• 679431-16-4 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-methanesulfonyl chloride 
• 679431-08-4 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-methanethiol 
• 679432-13-4 2-[1-(4-Chloro-benzenesulfonyl)-4-trifluoromethylsulfanylmethyl-cyclohexyl]-1,4-difluoro-benzene 

Relevant articles and documents

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The protease γ-secretase plays a pivotal role in the synthesis of pathogenic amyloid-β in Alzheimer's disease (AD). Here, we report a further extension to a series of cyclohexyl sulfone-based γ-secretase inhibitors which has allowed the preparation of hig