679432-13-4

Basic information

• Product Name: 2-[1-(4-Chloro-benzenesulfonyl)-4-trifluoromethylsulfanylmethyl-cyclohexyl]-1,4-difluoro-benzene
• CAS NO: 679432-13-4
• Molecular Weight: 484.939
• Mol File: 679432-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[1-(4-Chloro-benzenesulfonyl)-4-trifluoromethylsulfanylmethyl-cyclohexyl]-1,4-difluoro-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[1-(4-Chloro-benzenesulfonyl)-4-trifluoromethylsulfanylmethyl-cyclohexyl]-1,4-difluoro-benzene(679432-13-4)
• EPA Substance Registry System: 2-[1-(4-Chloro-benzenesulfonyl)-4-trifluoromethylsulfanylmethyl-cyclohexyl]-1,4-difluoro-benzene(679432-13-4)

Safety Data

• Hazardous Substances Data: 679432-13-4(Hazardous Substances Data)

Upstream product

• 471903-67-0 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid ethyl ester 
• 471903-66-9 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexylidene]-acetic acid ethyl ester 
• 471903-69-2 [4-(4-chloro-benzenesulfonyl)-4-(2,5-difluoro-phenyl)-cyclohexyl]-acetic acid 
• 471903-20-5 4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanone 
• 679431-06-2 2-[1-(4-Chloro-benzenesulfonyl)-4-iodomethyl-cyclohexyl]-1,4-difluoro-benzene 
• 1493-15-8 trifluoromethylsulfide 

Relevant articles and documents

4-Substituted cyclohexyl sulfones as potent, orally active γ-secretase inhibitors

The protease γ-secretase plays a pivotal role in the synthesis of pathogenic amyloid-β in Alzheimer's disease (AD). Here, we report a further extension to a series of cyclohexyl sulfone-based γ-secretase inhibitors which has allowed the preparation of hig