68399-81-5

Basic information

• Product Name: TAPSO
• Synonyms: 3-[N-Tris-(hydroxyMethyl)MethylaMino]-2-hydroxypropanesulphonic acid(TAPSO);TAPSO(2-Hydroxy-3-[tris(hydroxyMethylaMino]-1 propanesulfonic acid);TAPSO Vetec(TM) reagent grade, >=99%;N-[Tris(hydroxymethyl)metyl]-3-amino-2-hydroxypropanesulfonic acid;Tapso≥ 99.9% (titration);1-propanesulfonicacid,2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]ami;TAPSO;N-(TRIS(HYDROXYMETHYL)METHYL)-3-AMINO-2-HYDROXYPROPANE SULFONIC ACID
• CAS NO: 68399-81-5
• Molecular Formula: C₇H₁₇NO₇S
• Molecular Weight: 259.28
• EINECS: 269-993-8
• Product Categories: Biochemistry;Good's Buffers;Buffer
• Mol File: 68399-81-5.mol

Chemical Properties

• Melting Point: 224-229 °C (dec.)
• Appearance: Off-white to yellow/Powder
• Density: 1.601 g/cm³
• Refractive Index: 1.589
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: H2O: 1 M at 20 °C, clear, colorless
• PKA: 7.6(at 25℃)
• Water Solubility: soluble
• Merck: 13,9148
• BRN: 2113949
• CAS DataBase Reference: TAPSO(CAS DataBase Reference)
• NIST Chemistry Reference: TAPSO(68399-81-5)
• EPA Substance Registry System: TAPSO(68399-81-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• TSCA: Yes
• HazardClass: IRRITANT
• Hazardous Substances Data: 68399-81-5(Hazardous Substances Data)

Usage

Uses

Used in Biological and Biochemical Research:
TAPSO is used as a buffering agent for maintaining a stable pH environment in various biological and biochemical research applications. Its zwitterionic nature allows it to effectively buffer solutions without causing significant changes in pH, making it an ideal choice for experiments that require a neutral pH.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, TAPSO is used as a buffering agent in the formulation of drugs and other medicinal products. Its ability to maintain a stable pH environment is crucial for ensuring the stability and efficacy of these products.
Used in Diagnostics:
TAPSO is also used in the development of diagnostic tests and assays, where maintaining a stable pH is essential for accurate results.
Used in Cell Culture:
In cell culture applications, TAPSO is used as a buffering agent to provide a stable environment for cell growth and maintenance. Its neutral pH properties make it suitable for supporting the growth of various cell types.
Used in Enzyme Assays:
TAPSO is used as a buffering agent in enzyme assays, where maintaining a stable pH is crucial for the accurate measurement of enzyme activity.
Used in Protein Purification:
In protein purification processes, TAPSO is used as a buffering agent to maintain a stable pH environment, which is essential for the proper folding and function of proteins.
Used in Gene Expression Studies:
TAPSO is used as a buffering agent in gene expression studies, where maintaining a stable pH is important for the accurate measurement of gene expression levels.
Used in Molecular Biology:
In molecular biology research, TAPSO is used as a buffering agent in various applications, such as polymerase chain reaction (PCR) and DNA sequencing, where a stable pH is necessary for the proper functioning of enzymes and other biological molecules.

InChI:InChI=1/C7H17NO7S/c9-3-7(4-10,5-11)8-1-6(12)2-16(13,14)15/h6,8-12H,1-5H2,(H,13,14,15)/t6-/m0/s1

Relevant articles and documents

Amino-hydroxy-alkyl sulfonic acid zwitterions

Novel amino-hydroxy-alkylene sulfonic acid zwitterions are described which have the general formulas STR1 wherein A and B are each independently a hydrogen atom, an aliphatic, cycloaliphatic or hydroxyaliphatic group, N is one or two, and R=n is a cyclic radical comprising one or two ring nitrogen atoms, zero or one ring oxygen atoms and the remainder of the ring being carbon atoms, and water soluble salts of said acids. These organo-sulfonic acid compounds are useful as hydrogen ion buffers in biological research and particularly for tissue culture.