6842-78-0

Basic information

• Product Name: 4-Butoxybiphenyl
• Synonyms: 4-Butoxy-1,1'-biphenyl;4-Butoxybiphenyl;4-Biphenylyl butyl ether;NSC 68496;p-n-Butoxybiphenyl
• CAS NO: 6842-78-0
• Molecular Formula: C₁₆H₁₈O
• Molecular Weight: 226.31
• Mol File: 6842-78-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 70-72℃
• Boiling Point: 346℃
• Flash Point: 137℃
• Appearance: /
• Density: 0.991
• Vapor Pressure: 0.000123mmHg at 25°C
• Refractive Index: 1.538
• CAS DataBase Reference: 4-Butoxybiphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Butoxybiphenyl(6842-78-0)
• EPA Substance Registry System: 4-Butoxybiphenyl(6842-78-0)

Safety Data

• Hazardous Substances Data: 6842-78-0(Hazardous Substances Data)

Usage

General Description

4-Butoxybiphenyl, also known as 4-butylbiphenyl, is a chemical compound with the molecular formula C16H18O. It is classified as a biphenyl ether, which is a type of organic compound containing two phenyl rings connected by an oxygen atom. 4-Butoxybiphenyl is commonly used as a heat transfer fluid because of its high thermal stability and low volatility. It is also utilized as a synthetic intermediate in the production of various chemicals and pharmaceuticals. Additionally, this chemical has been studied for its potential use in liquid crystal displays and as a component in lubricants and plasticizers. Despite its various applications, 4-Butoxybiphenyl should be handled with care, as it may present hazards to human health and the environment.

InChI:InChI=1/C16H18O/c1-2-3-13-17-16-11-9-15(10-12-16)14-7-5-4-6-8-14/h4-12H,2-3,13H2,1H3

Upstream product

• 96227-74-6 (4-Butoxy-phenyl)-piperidin-1-yl-diazene 
• 71-43-2 benzene 
• 98-80-6 phenylboronic acid 
• 39969-57-8 1-bromo-4-butoxybenzene 
• 92-66-0 4-bromo-1,1'-biphenyl 
• 71-36-3 butan-1-ol 
• 2051-62-9 4'-biphenyl chloride 
• 52709-87-2 4'-butoxybiphenyl-4-carbonitrile 
• 92-88-6 4,4'-Dihydroxybiphenyl 
• 16881-71-3 4'-methoxy-1,1'-biphenyl-4-ol 
• 542-69-8 1-iodo-butane 
• 92-69-3 4-Phenylphenol 
• 84954-30-3 4-benzyloxybiphenyl 
• 96693-04-8 1-(n-butoxy)-4-iodobenzene 

Downstream Products

• 1345556-48-0 C₂₆H₂₆O₃ 
• 1345556-66-2 C₃₃H₄₀O₃ 
• 1345556-68-4 C₃₅H₄₄O₃ 
• 1345556-71-9 C₃₇H₄₈O₃ 
• 1345556-75-3 C₃₉H₅₂O₃ 
• 1345556-78-6 C₄₁H₅₆O₃ 
• 1345556-79-7 C₃₃H₃₀O₅ 
• 1345556-95-7 C₄₀H₄₄O₅ 
• 1345556-99-1 C₄₄H₅₂O₅ 
• 1345556-97-9 C₄₂H₄₈O₅ 
• 1345557-01-8 C₄₆H₅₆O₅ 
• 1345557-02-9 C₄₈H₆₀O₅ 
• 92-52-4 biphenyl 

Relevant articles and documents

Selective C-O Bond Reduction and Borylation of Aryl Ethers Catalyzed by a Rhodium-Aluminum Heterobimetallic Complex

We report the catalytic reduction of a C-O bond and the borylation by a rhodium complex bearing an X-Type PAlP pincer ligand. We have revealed the reaction mechanism based on the characterization of the reaction intermediate and deuterium-labeling experiments. Notably, this novel catalytic system shows steric-hindrance-dependent chemoselectivity that is distinct from conventional Ni-based catalysts and suggests a new strategy for selective C-O bond activation by heterobimetallic catalysis.

Light-Promoted Nickel Catalysis: Etherification of Aryl Electrophiles with Alcohols Catalyzed by a NiII-Aryl Complex

A highly effective C?O coupling reaction of (hetero)aryl electrophiles with primary and secondary alcohols is reported. Catalyzed by a NiII-aryl complex under long-wave UV (390–395 nm) irradiation in the presence of a soluble amine base without any additional photosensitizer, the reaction enables the etherification of aryl bromides and aryl chlorides as well as sulfonates with a wide range of primary and secondary aliphatic alcohols, affording synthetically important ethers. Intramolecular C?O coupling is also possible. The reaction appears to proceed via a NiI–NiIII catalytic cycle.

Amine-catalyzed direct photoarylation of unactivated arenes

Constructing biaryls through direct aromatic C-H functionalization of unactivated arenes has become a popular topic in organic chemistry. Many efficient methods have been developed. In this Communication, a direct arylation of unactivated arenes with a broad range of aryl iodides is reported. This reaction proceeds through a new type of amine-catalyzed single electron transfer initiated radical coupling procedure to form biaryls in high yields under UV irradiation at room temperature. Only 20 mol% of TMEDA is used as the catalyst. No other additives are required for this transformation, thus avoiding the use of toxic transition metal catalysts, strong bases, or large amounts of other organic additives. This greener protocol provides a new strategy to achieve direct aromatic C-H functionalization and offers a new example of cost-effective and environmentally benign access to biaryls. Copyright