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CAS

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684286-46-2

cis-Glimepiride, also known as Glimepiride EP Impurity A, is the cis-isomer of Glimepiride, a bulk drug substance. It is characterized by its off-white solid appearance and is distinguished from the trans-isomer by its spatial arrangement of atoms.

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  • 4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide

    Cas No: 684286-46-2

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  • 684286-46-2 Structure

  • Basic information

    1. Product Name: cis-Glimepiride
    2. Synonyms: cis-Glimepiride;cis-3-Ethyl-2,5-dihydro-4-Methyl-N-[2-[4-[[[[(cis-4-Methylcyclohexyl)aMino]carbonyl]aMino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxaMide;GliMepiride EP IMpurity A;3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[(cis-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxamide;1-[[p-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]phenyl]sulfonyl]-3-(cis-4-methylcyclohexyl)urea;Glimepiride Impurity (cis-isomer);Glimepiride EP impurity A -J;1-[4-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido) ethyl] phenylsulfonyl]-3-(4-cis-methylcyclohexyl)urea
    3. CAS NO:684286-46-2
    4. Molecular Formula: C24H34N4O5S
    5. Molecular Weight: 490.61556
    6. EINECS: N/A
    7. Product Categories: Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
    8. Mol File: 684286-46-2.mol

  • Chemical Properties

    1. Melting Point: 197-201°C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.29±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerator
    8. Solubility: Chloroform (Slightly), Methanol (Slightly, Heated)
    9. PKA: 5.10±0.10(Predicted)
    10. CAS DataBase Reference: cis-Glimepiride(CAS DataBase Reference)
    11. NIST Chemistry Reference: cis-Glimepiride(684286-46-2)
    12. EPA Substance Registry System: cis-Glimepiride(684286-46-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 684286-46-2(Hazardous Substances Data)

684286-46-2 Usage

Uses

Used in Pharmaceutical Industry:
cis-Glimepiride is used as an impurity in the production of Glimepiride, a medication used to treat type 2 diabetes. It is essential to monitor and control the presence of this impurity to ensure the safety, efficacy, and quality of the final drug product.
Used in Quality Control and Research:
cis-Glimepiride is utilized as a reference compound in the quality control and analytical testing of Glimepiride formulations. It aids in the identification, quantification, and assessment of impurities in the drug substance, contributing to the overall quality and reliability of the medication.
Used in Drug Development:
As a cis-isomer of Glimepiride, cis-Glimepiride may be investigated for its potential therapeutic applications and properties. Research into its pharmacological effects and interactions can provide valuable insights into the development of new drugs or the improvement of existing treatments for various conditions, including diabetes.

Check Digit Verification of cas no

The CAS Registry Mumber 684286-46-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,4,2,8 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 684286-46:
(8*6)+(7*8)+(6*4)+(5*2)+(4*8)+(3*6)+(2*4)+(1*6)=202
202 % 10 = 2
So 684286-46-2 is a valid CAS Registry Number.

684286-46-2 Well-known Company Product Price

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  • USP

  • (1292314)  Glimepiride Related Compound A  United States Pharmacopeia (USP) Reference Standard

  • 684286-46-2

  • 1292314-20MG

  • 14,578.20CNY

  • Detail

684286-46-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-ethyl-3-methyl-N-[2-[4-[(4-methylcyclohexyl)carbamoylsulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide

1.2 Other means of identification

Product number -
Other names Amarel

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:684286-46-2 SDS

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