687981-26-6

Basic information

• Product Name: 3-Oxo-2-phenyl-butyrimidic acid ethyl ester
• Synonyms: 3-Oxo-2-phenyl-butyrimidic acid ethyl ester
• CAS NO: 687981-26-6
• Molecular Weight: 205.257
• Mol File: 687981-26-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Oxo-2-phenyl-butyrimidic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxo-2-phenyl-butyrimidic acid ethyl ester(687981-26-6)
• EPA Substance Registry System: 3-Oxo-2-phenyl-butyrimidic acid ethyl ester(687981-26-6)

Safety Data

• Hazardous Substances Data: 687981-26-6(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 4468-48-8 1-phenyl-1-cyanopropan-2-one 

Downstream Products

• 132332-38-8 3-{3-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-propyl}-6-methyl-5-phenyl-1H-pyrimidine-2,4-dione 
• 132332-37-7 3-{2-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-ethyl}-6-methyl-5-phenyl-1H-pyrimidine-2,4-dione 
• 132332-36-6 6-methyl-5-phenyl-2,4(1H,3H)-pyrimidinedione 
• 116608-91-4 6-methyl-5-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-4-one 
• 5413-05-8 ethyl 2-phenylacetoacetate 

Relevant articles and documents

Oxidative aromatic C-O bond formation: synthesis of 3-functionalized benzo[b]furans by FeCl3-mediated ring closure of a-Aryl ketones

A variety of 3-functionalized benzo[b]furans were achieved by way of a FeCl3-medlated Intramolecular cyclization of electron-rich a-aryl ketones. The alkoxy substituent on the benzene ring In the substrates was essential for an efficient cyclization to occur. This novel method allows the construction of benzo[b]furan rings by joining the O-atom on the side chain to the benzene ring via direct oxidative aromatic C-O bond formation.