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68844-05-3

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68844-05-3 Usage

General Description

(S)-3-Phenyl-4-hydroxybutyric acid 1,4-lactone is a chemical compound that is a lactone derivative of (S)-3-phenyl-4-hydroxybutyric acid. It is known for its chiral properties and is used in the pharmaceutical industry for the synthesis of chiral drugs and other biologically active compounds. (S)-3-Phenyl-4-hydroxybutyric acid 1,4-lactone has potential applications in the development of new pharmaceuticals, particularly in the area of cardiovascular and central nervous system disorders. Additionally, it has been studied for its potential antioxidant and anticancer properties, making it an interesting compound for further research and development.

Check Digit Verification of cas no

The CAS Registry Mumber 68844-05-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,8,8,4 and 4 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 68844-05:
(7*6)+(6*8)+(5*8)+(4*4)+(3*4)+(2*0)+(1*5)=163
163 % 10 = 3
So 68844-05-3 is a valid CAS Registry Number.

68844-05-3Relevant articles and documents

Chiral Synthesis of 3-Substituted and 3,3-Disubstituted γ-Butyrolactones by Enantioselective Deprotonation Strategy

Honda, Toshio,Kimura, Nobuaki,Tsubuki, Masayoshi

, p. 1475 - 1478 (1993)

Chiral synthesis of 3-substituted and 3,3-disubstituted γ-butyrolactones was achieved by employing an enantioselctive deprotonation of the corresponding cyclobutanone derivatives with chiral bases as a key reaction.

Asymmetric Conjugate Addition of Chiral Secondary Borylalkyl Copper Species

Jang, Won Jun,Woo, Jeongkyu,Yun, Jaesook

supporting information, p. 4614 - 4618 (2021/01/18)

We report the diastereo- and enantioselective conjugate addition of chiral secondary borylalkyl copper species derived from borylalkenes in situ to α,β-unsaturated diesters. In the presence of a chiral bisphosphine-ligated CuH catalyst, the conjugate addition provides a direct access to enantioenriched alkylboron compounds containing two contiguous carbon stereogenic centers in good yield with high diastereo- and enantioselectivity (up to >98:2 dr, >99:1 er) by assembling readily available starting alkenyl reagents in a single operation without using preformed organometallic reagents or chiral auxiliaries. The resulting products were used in various organic transformations. The utility of the synthetic approach was highlighted by the synthesis of (?)-phaseolinic acid.

Investigation of a New Type I Baeyer–Villiger Monooxygenase from Amycolatopsis thermoflava Revealed High Thermodynamic but Limited Kinetic Stability

Mansouri, Hamid R.,Mihovilovic, Marko D.,Rudroff, Florian

, p. 971 - 977 (2020/01/22)

Baeyer–Villiger monooxygenases (BVMOs) are remarkable biocatalysts, but, due to their low stability, their application in industry is hampered. Thus, there is a high demand to expand on the diversity and increase the stability of this class of enzyme. Sta

Phosphothreonine (pThr)-Based Multifunctional Peptide Catalysis for Asymmetric Baeyer-Villiger Oxidations of Cyclobutanones

Featherston, Aaron L.,Shugrue, Christopher R.,Mercado, Brandon Q.,Miller, Scott J.

, p. 242 - 252 (2019/01/04)

Biologically inspired phosphothreonine (pThr)-embedded peptides that function as chiral Br?nsted acid catalysts for enantioselective Baeyer-Villiger oxidations (BV) of cyclobutanones with aqueous H2O2 are reported herein. Complementa

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