6888-79-5

Basic information

• Product Name: Benzene, 1-bromo-4-(1-methylethenyl)-
• CAS NO: 6888-79-5
• Molecular Formula: C9H9Br
• Molecular Weight: 197.074
• Mol File: 6888-79-5.mol
• Article Data: 73

Chemical Properties

• CAS DataBase Reference: Benzene, 1-bromo-4-(1-methylethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-bromo-4-(1-methylethenyl)-(6888-79-5)
• EPA Substance Registry System: Benzene, 1-bromo-4-(1-methylethenyl)-(6888-79-5)

Safety Data

• Hazardous Substances Data: 6888-79-5(Hazardous Substances Data)

Upstream product

• 99-90-1 para-bromoacetophenone 
• 32454-35-6 2-(4-bromophenyl)-2-methylpropionic acid 
• 4519-28-2 tetramethylphosphonium bromide 
• 75-24-1 trimethylaluminum 
• 586-75-4 4-chlorobenzoyl chloride 
• 67-71-0 dimethylsulfone 
• 873-75-6 4-bromobenzenemethanol 
• 1031-15-8 methyltriphenylphosphonium chloride 
• 39598-55-5 (bromomethylene)triphenylphosphorane 
• 586-61-8 4-iso-propylbromobenzene 
• 61078-14-6 1-methyl-2-(methylsulfonyl)-1H-benzo[d]imidazole 
• 98-82-8 Isopropylbenzene 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 18620-02-5 (4-bromophenyl)magnesium bromide 

Downstream Products

• 50-00-0 formaldehyd 
• 99-90-1 para-bromoacetophenone 
• 80909-78-0 p-bromo-α-methylstyrene oxide 
• 2077-19-2 2-(4-bromophenyl)propan-2-ol 
• 67595-62-4 1-(4-bromophenyl)-1-methylethylium 
• 1092399-42-2 (R)-ethyl 4-(4-bromophenyl)-2-hydroxypent-4-enoate 
• 1254470-59-1 N-[2-(4-bromophenyl)prop-2-en-1-yl]-N-(p-toluenesulfonyl)amide 
• 1262985-40-9 2-[(2S)-2-(4-bromophenyl)propyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1440956-86-4 1-bromo-4-(1-methylcycloprop-2-en-1-yl)benzene 

Relevant articles and documents

A donor-acceptor complex enables the synthesis of: E -olefins from alcohols, amines and carboxylic acids

Olefins are prevalent substrates and functionalities. The synthesis of olefins from readily available starting materials such as alcohols, amines and carboxylic acids is of great significance to address the sustainability concerns in organic synthesis. Metallaphotoredox-catalyzed defunctionalizations were reported to achieve such transformations under mild conditions. However, all these valuable strategies require a transition metal catalyst, a ligand or an expensive photocatalyst, with the challenges of controlling the region- and stereoselectivities remaining. Herein, we present a fundamentally distinct strategy enabled by electron donor-acceptor (EDA) complexes, for the selective synthesis of olefins from these simple and easily available starting materials. The conversions took place via photoactivation of the EDA complexes of the activated substrates with alkali salts, followed by hydrogen atom elimination from in situ generated alkyl radicals. This method is operationally simple and straightforward and free of photocatalysts and transition-metals, and shows high regio- and stereoselectivities.

Formal Allylation and Enantioselective Cyclopropanation of Donor/Acceptor Rhodium(II) Azavinyl Carbenes

A highly efficient formal allylation of dihydronaphthotriazoles with alkenes under rhodium(II) catalysis is reported. Various allyl dihydronaphthalene derivatives were furnished via rhodium(II) azavinyl carbenes with moderate to good yields and excellent chemoselectivity. When monosubstituted alkenes are used, cyclopropanation occurs and good to excellent enantioselectivities have been achieved. Particularly noteworthy is the allylic C(sp2)-H activation instead of traditional C(sp3)-H activation in the formal allylation process.

Ni-Catalyzed Reductive Allylation of α-Chloroboronates to Access Homoallylic Boronates

The transition-metal-catalyzed allylation reaction is an efficient strategy for the construction of new carbon-carbon bonds alongside allyl or homoallylic functionalization. Herein we describe a Ni-catalyzed reductive allylation of α-chloroboronates to efficiently render the corresponding homoallylic boronates, which could be readily converted into valuable homoallylic alcohols or amines or 1,4-diboronates. This reaction features a broad substrate scope with good functional group compatibility that is complementary to the existing methods for the preparation of homoallylic boronates.