69655-50-1

Basic information

• Product Name: 4',7-di-O-methyl-puerarin
• Synonyms: 4',7-di-O-methyl-puerarin
• CAS NO: 69655-50-1
• Molecular Weight: 444.438
• Mol File: 69655-50-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4',7-di-O-methyl-puerarin(CAS DataBase Reference)
• NIST Chemistry Reference: 4',7-di-O-methyl-puerarin(69655-50-1)
• EPA Substance Registry System: 4',7-di-O-methyl-puerarin(69655-50-1)

Safety Data

• Hazardous Substances Data: 69655-50-1(Hazardous Substances Data)

Upstream product

• 69667-95-4 Acetic acid (2S,3S,4R,5R,6R)-4,5-diacetoxy-2-{2-acetoxy-6-methoxy-3-[(E)-3-(4-methoxy-phenyl)-acryloyl]-phenyl}-6-acetoxymethyl-tetrahydro-pyran-3-yl ester 
• 3681-99-0 puerarin 
• 74-88-4 methyl iodide 

Downstream Products

• 3681-99-0 puerarin 

Relevant articles and documents

Glucose uptake enhancing activity of puerarin and the role of C-glucoside suggested from activity of related compounds

Chemical treatment of diabetes mellitus is widely studied and controlling of blood glucose level is the main course of therapy. In type 2 diabetes mellitus, insulin resistance is the major problem. An isoflavone C-glucoside, puerarin (1), is known to enhance glucose uptake into the insulin sensitive cell and is thought to be a candidate for treatment of diabetes mellitus. We synthesized 1 and several derivatives to apply for the structure-activity relationship study. The result against 3T3-L1 adipocyte indicated that the C-glucoside part of 1 is unconcerned in its activity when tested in vitro and the main structure responsible for its activity was the isoflavone moiety.