6999-03-7Relevant articles and documents
Synthesis of new monofunctional organosilicon molecules - Prospective efficient stoppers for the design of new siloxane polymers of unusual architecture
Anisimov, Anton A.,Kononevich, Yuriy N.,Korlyukov, Alexander A.,Arkhipov, Dmitry E.,Kononova, Elena G.,Peregudov, Alexander S.,Shchegolikhina, Olga I.,Muzafarov, Aziz M.
, p. 79 - 83 (2014)
The work reports the synthesis and characterization of new previously unknown bulk polyfunctional organosilanes with rigid molecular structure. The molecular structures of compounds 3 and 4 were defined by X-ray data. The possibility of use of prepared co
Orthogonal Stability and Reactivity of Aryl Germanes Enables Rapid and Selective (Multi)Halogenations
Deckers, Kristina,Fricke, Christoph,Schoenebeck, Franziska
supporting information, p. 18717 - 18722 (2020/08/25)
While halogenation is of key importance in synthesis and radioimaging, the currently available repertoire is largely designed to introduce a single halogen per molecule. This report makes the selective introduction of several different halogens accessible. Showcased here is the privileged stability of nontoxic aryl germanes under harsh fluorination conditions (that allow selective fluorination in their presence), while displaying superior reactivity and functional-group tolerance in electrophilic iodinations and brominations, outcompeting silanes or boronic esters under rapid and additive-free conditions. Mechanistic experiments and computational studies suggest a concerted electrophilic aromatic substitution as the underlying mechanism.
Design, synthesis and acaricidal activities of Cyflumetofen analogues based on carbon-silicon isosteric replacement
Beadle, Ryan,Cheng, Jiagao,Earley, Fergus G.,Li, Zhong,Maienfisch, Peter,Zhou, Cong
, (2020/04/30)
The application of a carbon-silicon bioisosteric replacement strategy to find new acaricides with improved properties led to the discovery of Sila-Cyflumetofen 6B, a novel and highly potent acaricide. The essential t-butyl group in the beta-ketonitrile ac