70215-04-2

Basic information

• Product Name: (+/-)-2-HYDROXYNONANOIC ACID
• Synonyms: ALPHA-HYDROXY NONANOIC ACID;(+/-)-2-HYDROXYNONANOIC ACID;(+/-)-2-Hydroxyninanoic acid
• CAS NO: 70215-04-2
• Molecular Formula: C₉H₁₈O₃
• Molecular Weight: 174.24
• Mol File: 70215-04-2.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 303.9°C at 760 mmHg
• Flash Point: 151.8°C
• Appearance: /
• Density: 1.027g/cm³
• Vapor Pressure: 8.64E-05mmHg at 25°C
• Refractive Index: 1.464
• CAS DataBase Reference: (+/-)-2-HYDROXYNONANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-2-HYDROXYNONANOIC ACID(70215-04-2)
• EPA Substance Registry System: (+/-)-2-HYDROXYNONANOIC ACID(70215-04-2)

Safety Data

• Hazardous Substances Data: 70215-04-2(Hazardous Substances Data)

Usage

General Description

(+/-)-2-Hydroxynonanoic acid is a chemical compound that exists in two stereoisomeric forms, denoted as (+) and (-). It is a nine-carbon hydroxy fatty acid that is commonly found in various natural sources such as human body fluids, plants, and microorganisms. (+/-)-2-HYDROXYNONANOIC ACID has been shown to exhibit anti-inflammatory and immunomodulatory properties, making it a potential therapeutic agent for various conditions such as inflammation-related diseases and autoimmune disorders. Additionally, it has the potential to serve as a precursor in the synthesis of various pharmaceuticals and biologically active compounds. The chemical structure and properties of (+/-)-2-Hydroxynonanoic acid make it a valuable molecule in the fields of biotechnology, medicine, and organic chemistry.

InChI:InChI=1/C9H18O3/c1-2-3-4-5-6-7-8(10)9(11)12/h8,10H,2-7H2,1H3,(H,11,12)

Upstream product

• 112-05-0 nonanoic acid 
• 104228-12-8 2-Butyryloxy-nonanoic acid ethyl ester 
• 137152-54-6 3-heptyloxirane-2,2-dicarbonitrile 
• 124838-41-1 S-methyl 2-hydroxynonanethioate 
• 7425-60-7 2-bromo-n-nonanoic acid ethyl ester 
• 592-76-7 1-Heptene 
• 1301234-58-1 C₁₃H₂₇NO₂ 
• 124-13-0 Octanal 
• 13125-66-1 n-heptylmagnesium bromide 
• 116296-93-6 2-hydroxy-nonanenitrile 
• 145090-39-7 S-methyl-2-acetoxythiononanoate 
• 104228-19-5 2-Butyryloxy-nonanoic acid methyl ester 
• 104228-11-7 2-Propionyloxy-nonanoic acid ethyl ester 
• 104228-18-4 2-Propionyloxy-nonanoic acid methyl ester 

Downstream Products

• 124-13-0 Octanal 
• 109856-84-0 (S)-(-)-2-heptyloxirane 
• 111423-28-0 (S)-nonane-1,2-diol 
• 133444-84-5 (S)-2-amino-nonanoic acid 
• 14952-06-8 methyl (2E)-2-nonenoate 
• 143993-00-4 2-hydroxy-nonanoic acid anilide 

Relevant articles and documents

Preparative Asymmetric Synthesis of Canonical and Non-canonical a-amino Acids through Formal Enantioselective Biocatalytic Amination of Carboxylic Acids

Chemical and biocatalytic synthesis of non-canonical a-amino acids (ncAAs) from renewable feedstocks and using mild reaction conditions has not efficiently been solved. Here, we show the development of a three-step, scalable and modular one-pot biocascade for linear conversion of renewable fatty acids (FAs) into enantiopure l-a-amino acids. In module 1, selective a-hydroxylation of FAs is catalyzed by the P450 peroxygenase P450CLA. By using an automated H2O2 supplementation system, efficient conversion (46 to >99%; TTN>3300) of a broad range of FAs (C6:0 to C16:0) into valuable a-hydroxy acids (a-HAs; >90% a-selective) is shown on preparative scale (up to 2.3 gL1 isolated product). In module 2, a redox-neutral hydrogen borrowing cascade (alcohol dehydrogenase/amino acid dehydrogenase) allowed further conversion of a-HAs into l-a-AAs (20 to 99%). Enantiopure l-a-AAs (e.e. >99%) including the pharma synthon l-homo-phenylalanine can be obtained at product titers of up to 2.5 gL1. Based on renewables and excellent atom economy, this biocascade is among the shortest and greenest synthetic routes to structurally diverse and industrially relevant ncAAs.

Metal-free one-pot α-carboxylation of primary alcohols

An efficient metal-free procedure for the formal α-carboxylation of primary alcohols has been developed. The method involves a one-pot oxidation/Passerini/hydrolysis sequence and provides access to α-hydroxy acids bearing a broad range of functional groups. A minor modification to the reaction conditions extends the range of accessible products to α-hydroxy esters.

SHORT CHAIN 2-HYDROXYCARBOXYLIC ACID-BASED DERIVATIVES OF CERAMIDES

The present invention relates to active ceramide derivatives. Specifically, the invention relates to 2(alpha)-hydroxycarboxylic acid-based ceramide derivatives. The present invention describes a method for obtaining these compounds. The invention also relates to the use of these compounds in cosmetic compositions.