70218-65-4

Basic information

• Product Name: 1-amino-4-phenylpiperazine-2,5-dione
• Synonyms: 2,5-Piperazinedione, 1-amino-4-phenyl-
• CAS NO: 70218-65-4
• Molecular Formula: C₁₀H₁₁N₃O₂
• Molecular Weight: 205.2132
• Mol File: 70218-65-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 483.2°C at 760 mmHg
• Flash Point: 246°C
• Density: 1.338g/cm³
• Vapor Pressure: 1.72E-09mmHg at 25°C
• Refractive Index: 1.619
• CAS DataBase Reference: 1-amino-4-phenylpiperazine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-amino-4-phenylpiperazine-2,5-dione(70218-65-4)
• EPA Substance Registry System: 1-amino-4-phenylpiperazine-2,5-dione(70218-65-4)

Safety Data

• Hazardous Substances Data: 70218-65-4(Hazardous Substances Data)

Usage

Abbreviation

PPD

Chemical structure

Piperazine derivative with a phenyl group and a piperazine ring

Physical appearance

White crystalline solid

Known metabolite

Antidepressant drug Trazodone

Biological activity

Central nervous system

Potential applications

Drug candidate for the treatment of neurological disorders

Research status

Further research needed to understand pharmacological properties and potential applications

Upstream product

• 62-53-3 aniline 
• 2216-92-4 N-phenylglycine ethyl ester 
• 51114-26-2 N-chloroacetyl-N-phenylglycine ethyl ester 

Relevant articles and documents

Piperazin-2,5-diones N,N'-substituted. III. Synthesis and pharmacological activities of some 1-aryl-4-arylidene (or heteroarylidene)aminopiperazin-2,5-dione derivatives

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