7081-53-0 Usage
Uses
Used in Pharmaceutical Industry:
Doxapram hydrochloride monohydrate is used as a respiratory stimulant for increasing respiration in patients with chronic pulmonary disease, respiratory depression induced by drug overdose, and to stimulate deep breathing post-anesthesia.
Used in Antibacterial Applications:
Doxapram hydrochloride monohydrate is used as an antibacterial agent to combat bacterial infections.
Clinical Use
Postoperative respiratory depressionAcute respiratory failure
Drug interactions
Potentially hazardous interactions with other drugsAnaesthetics: increased risk of arrhythmias with
volatile liquid general anaesthetics - avoid for at least
10 minutes after volatile liquid general anaesthetics.
Metabolism
Doxapram is extensively metabolised in the liver, and
the major route of excretion of metabolites and a small
amount of unchanged drug is thought to be via bile to the
faeces.
Check Digit Verification of cas no
The CAS Registry Mumber 7081-53-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,0,8 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 7081-53:
(6*7)+(5*0)+(4*8)+(3*1)+(2*5)+(1*3)=90
90 % 10 = 0
So 7081-53-0 is a valid CAS Registry Number.
InChI:InChI=1/C24H30N2O2.ClH.H2O/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;;/h3-12,22H,2,13-19H2,1H3;1H;1H2
