7132-64-1Relevant articles and documents
Structures of nine oxygenated 4-methylene sterols from Hachijo marine sponge Theonella swinhoei
Sugo, Yumi,Inouye, Yoshinobu,Nakayama, Noboru
, p. 738 - 742 (1995)
Nine new sterols have been isolated from a marine sponge, Theonella swinhoei.Of these, seven sterols were found to be conicasterol derivatives oxygenated at carbon-7 and/or carbon-15.The other two were (24R)-7β,8β-epoxy-14α-methoxy-4-methylene-24-methylcholestan-3β-ol and (24R)-8,14-seco-8,14-dioxo-4-methylene-24-methylcholestan-3β-ol. - Keywords: marine sterol; 4-methylene sterol; conicasterol derivatives; Theonella swinhoei; marine sponge
New ingenane and ingol diterpenoids from Euphorbia royleana
Gan, Lu,Su, Tong,Wei, Xun,Wu, Shuqi,Yin, Sheng
, (2021/11/10)
Phytochemical investigation on the 95% EtOH extract of the Traditional Chinese Medicine (TCM) Euphorbia royleana (Ba-wang-bian in Chinese) led to the isolation of 11 diterpenoids (1–11) and two triterpenoids (12 and 13). Among them, compounds 1 and 2 were new ingenane and ingol diterpenoids, respectively. Their structures were elucidated by a combination of spectroscopic analyses (1 D and 2 D NMR, HRMS, ECD, UV, and IR data) and chemical methods. Compounds 12 and 13 exhibited moderate cytotoxicities in vitro against human lung cancer cell line A549 with IC50 values of 14.84 ± 0.56 and 27.11 ± 1.65 μM, respectively.
Visible light-driven Giese reaction with alkyl tosylates catalysed by nucleophilic cobalt
Komeyama, Kimihiro,Michiyuki, Takuya,Teshima, Yoshikazu,Osaka, Itaru
, p. 3539 - 3546 (2021/02/03)
The scope of the Giese reaction is expanded using readily available alkyl tosylates as substrates and nucleophilic cobalt(i) catalysts under visible-light irradiation. The reaction proceeds preferentially with less bulky primary alkyl tosylates. This unique reactivity enables the regio-selective Giese reaction of polyol derivatives.
Dammarane triterpenoids from Carnauba, Copernicia prunifera (Miller) H. E. Moore (Arecaceae), wax
De Almeida, Buana C.,Araújo, Bruno Q.,Barros, Elcio D. S.,Freitas, Samya D. L.,Maciel, Dayany S. A.,Ferreira, Ari J. S.,Guadagnin, Rafael C.,Vieira, Gerardo M.,Lago, Jo?o H. G.,Chaves, Mariana H.
, p. 1371 - 1376 (2017/07/13)
Phytochemical investigation from carnauba (Copernicia prunifera) wax led to the identification of sixteen dammarane–type triterpenes, including thirteen new characterized as: (24R*)-methyldammara-20,25-dien-3α-ol and a mixture of alkyl (24R*)-methyldammar-25-en-20-ol-3β-carboxylates, together with three previously described triterpenes: carnaubadiol, (24R*)-methyldammara-20,25-dien-3β-ol and (24R*)-24-methyldammara-20,25-dien-3-one. Moreover, four fatty alcohols (eicosanol, docosanol, tetracosanol and hexacosanol) as well as four sterols (cholesterol, campesterol, stigmasterol, and sitosterol) were also obtained. These compounds were isolated using classical chromatographic methods and their structures were determined by spectroscopic and chemical methods.