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7250-67-1

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7250-67-1 Usage

Uses

Different sources of media describe the Uses of 7250-67-1 differently. You can refer to the following data:
1. 1-(2-Chloroethyl)pyrrolidine is a haloalkyl substituted pyrrolidine used in the preparation of various pharmaceutical compound such as the estrogen receptor antagonist Nafoxidine (N212800) and its ana logues.
2. 1-(2-Chloroethyl)pyrrolidine is a haloalkyl substituted pyrrolidine used in the preparation of various pharmaceutical compound such as the estrogen receptor antagonist Nafoxidine (N212800) and its analogues.

Purification Methods

Purify the hydrochloride by recrystallisation from isopropanol/di-isopropyl ether (charcoal) and recrystallise it twice more. The free base, b 55-56o/11mm, 60-63o/23mm and 90o/56mm, is relatively unstable and should be converted to the hydrochloride immediately, by dissolving in isopropanol and bubbling dry HCl through the solution at 0o, filtering off the hydrochloride and recrystallising it. The picrate has m 107.3-107.8o (from EtOH) [Cason J Org Chem 24 247 1959, Wright et al. J Am Chem Soc 70 3098 1948]. [Beilstein 20 III/IV 66.]

Check Digit Verification of cas no

The CAS Registry Mumber 7250-67-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,5 and 0 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 7250-67:
(6*7)+(5*2)+(4*5)+(3*0)+(2*6)+(1*7)=91
91 % 10 = 1
So 7250-67-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H12ClN/c7-3-6-8-4-1-2-5-8/h1-6H2/p+1

7250-67-1 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
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  • Detail
  • Alfa Aesar

  • (B22236)  1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%   

  • 7250-67-1

  • 25g

  • 461.0CNY

  • Detail
  • Alfa Aesar

  • (B22236)  1-(2-Chloroethyl)pyrrolidine hydrochloride, 98%   

  • 7250-67-1

  • 100g

  • 1761.0CNY

  • Detail
  • Aldrich

  • (C42807)  1-(2-Chloroethyl)pyrrolidinehydrochloride  98%

  • 7250-67-1

  • C42807-25G

  • 459.81CNY

  • Detail
  • Aldrich

  • (C42807)  1-(2-Chloroethyl)pyrrolidinehydrochloride  98%

  • 7250-67-1

  • C42807-100G

  • 1,819.35CNY

  • Detail

7250-67-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-Chloroethyl)pyrrolidine hydrochloride

1.2 Other means of identification

Product number -
Other names 1-(2-chloroethyl)pyrrolidine,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7250-67-1 SDS

7250-67-1Relevant articles and documents

Coumadin female phenol split-ring analogue and its medical use

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Paragraph 0033-0035, (2017/10/06)

The invention relates to the field of pharmaceutical chemistry, in particular to a coumestrol open-ring analogue with structures as shown in general formulae I and II and a medical application thereof, especially an application to the preparation of drugs as angiogenesis inhibition and vascular disruption agents.

INDENOISOQUINOLINONE DERIVATIVES, MANUFACTURING METHOD AND MEDICAL USE THEREOF

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Paragraph 0068; 0069, (2013/04/13)

Indenoisoquinolinone derivatives (I), the manufacturing method and the medical use thereof, which belong to pharmaceutical chemistry and organic chemistry field, are disclosed. These compounds can be used for treating several medical symptoms related to postmenopausal syndrome, uterine fibers deterioration and aortic smooth muscle cells proliferation, especially ER-(+) depend breast cancer. Meanwhile, these compounds can also be used for treating glioma and lung cancer, and have inhibiting effect on tumor metastasis effect on tumor metastasis.

Benzimidazolone antiviral agents

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, (2008/06/13)

The present invention concerns antiviral compounds, their compositions, and use in the treatment of viral infections. More particularly, the invention provides benzimidazolone derivatives for the treatment of respiratory syncytial virus infection.

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