72842-25-2

Basic information

• Product Name: DI-(4-TOLUOYL)-L-TARTARIC ANHYDRIDE
• Synonyms: DI-(4-TOLUOYL)-L-TARTARIC ANHYDRIDE;DI-P-TOLUOYL-L-TARTARIC ANHYDRIDE;L-PTAN
• CAS NO: 72842-25-2
• Molecular Formula: C₂₀H₁₆O₇
• Molecular Weight: 368.34
• Mol File: 72842-25-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: DI-(4-TOLUOYL)-L-TARTARIC ANHYDRIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DI-(4-TOLUOYL)-L-TARTARIC ANHYDRIDE(72842-25-2)
• EPA Substance Registry System: DI-(4-TOLUOYL)-L-TARTARIC ANHYDRIDE(72842-25-2)

Safety Data

• Hazardous Substances Data: 72842-25-2(Hazardous Substances Data)

Upstream product

• 147-71-7 D-tartaric acid 
• 106-43-4 para-chlorotoluene 
• 87-69-4 L-Tartaric acid 
• 133-37-9 DL-tartaric acid 
• 32634-68-7 (2S,3S)-di-4-toluoyltartaric acid 
• 874-60-2 4-methyl-benzoyl chloride 

Downstream Products

• 32634-68-7 (2S,3S)-di-4-toluoyltartaric acid 
• 32634-66-5 Di-p-toluoyl-L-tartaric acid 

Relevant articles and documents

METHOD OF PREPARING (3R,4S)-3-ACETAMIDO-4-ALLYL-N-(TERT-BUTYL)PYRROLIDINE-3-CARBOXAMIDE

A method is provided to conveniently separate racemic (3R,4S)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide and (3S,4R)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide using selective crystallization with chiral carboxylic acids.

Resolution of (+/-)-propranolol.

Two improvements in propranolol resolution were developed. Both the (+)- and (-)-di-(p-toluoyl)tartaric acids were used as the resolving agents. This procedure reduced the number of crystallizations needed to obtain a pure product. Furthermore, synthesis of the resolving agent was improved.