73223-83-3

Basic information

• Product Name: 1,4-dioxaspiro[4.5]decan-9-ol
• Synonyms: 1,4-dioxaspiro[4.5]decan-7-ol
• CAS NO: 73223-83-3
• Molecular Formula: C₈H₁₄O₃
• Molecular Weight: 158.195
• Mol File: 73223-83-3.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 286.935°C at 760 mmHg
• Flash Point: 127.334°C
• Density: 1.174g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.506
• CAS DataBase Reference: 1,4-dioxaspiro[4.5]decan-9-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-dioxaspiro[4.5]decan-9-ol(73223-83-3)
• EPA Substance Registry System: 1,4-dioxaspiro[4.5]decan-9-ol(73223-83-3)

Safety Data

• Hazardous Substances Data: 73223-83-3(Hazardous Substances Data)

Usage

Structure

Cyclic ether containing a tetrahydropyran ring and a hydroxyl group

Usage

Building block in organic synthesis

Applications

Production of pharmaceuticals, agrochemicals, and fragrances

Additional use

Solvent in various chemical processes

Sensory property

Pleasant odor

Industry

Flavor and fragrance industry

Stability

Relatively stable compound

Reactivity

Low reactivity

Industrial value

Versatile and valuable chemical in various industrial applications

Upstream product

• 1004-58-6 1,4-dioxa-spiro[4.5]dec-6-ene 
• 4969-01-1 1,4-dioxaspiro[4.5]decan-7-one 
• 504-02-9 1,3-cylohexanedione 
• 1728-15-0 (R,S)-6-bromo-1,4-dioxaspiro<4.5>decane 
• 19770-37-7 6,7-epoxy-1,4-dioxaspiro<4,5>decane 

Downstream Products

• 4969-01-1 1,4-dioxaspiro[4.5]decan-7-one 
• 123990-98-7 3-benzyloxycyclohexan-1-one 
• 141120-33-4 8-methylsulfonyloxy-1,4-dioxaspiro[4.5]decane 
• 1372627-00-3 C₁₃H₁₅F₂N₅O 
• 1372627-49-0 C₁₃H₁₅N₅O₂ 
• 1459-31-0 2-cyclohexenone 2,4-dinitrophenylhydrazone 

Relevant articles and documents

Stereoelectronic Model to Explain Highly Stereoselective Reactions of Seven-Membered-Ring Oxocarbenium-Ion Intermediates

Nucleophilic attack on seven-membered-ring oxocarbenium ions is generally highly stereoselective. The preferred mode of nucleophilic attack forms the product in a conformation that minimizes transannular interactions, thus leading to different stereoselectivity as compared to that of reactions involving six-membered-ring oxocarbenium ions.

REGIOSELECTIVE REDUCTIONS OF 2,3-EPOXY ACETALS WITH ZINC-CHLOROTRIMETHYLSILANE AND LITHIUM ALUMINIUM HYDRIDE: CONVENIENT SYNTHESIS OF 1,2 AND 1,3-DIONES

A variety of 2,3-epoxy acetals have been found to undergo regioselective reductions with zinc-chlorotrimethylsilane and lithium aluminium hydride to give 2-hydroxy and 3-hydroxy acetals respectively.Their oxidation followed by hydrolysis furnished the corresponding 1,2- and 1,3-diones in good yields.