73290-22-9

Basic information

• Product Name: 2-Bromo-5-iodopyridine
• Synonyms: 2-Bromo-5-iodopyridine,97%;2-Bromo-5-iodopyridine 96%;2-BROMO-5-IODOPYRIDINE
• CAS NO: 73290-22-9
• Molecular Formula: C₅H₃BrIN
• Molecular Weight: 283.89
• EINECS: -0
• Product Categories: Pyridine;Halides;Pyridines;Heterocycle;Boronic Acid;C5Heterocyclic Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;Propidium heterocyclic series;Pyridine Series;Heterocycle-Pyridine series
• Mol File: 73290-22-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 121-123 °C(lit.)
• Boiling Point: 278.6 °C at 760 mmHg
• Flash Point: 122.3 °C
• Appearance: White to off-white/Powder
• Density: 2.347 g/cm³
• Vapor Pressure: 0.00714mmHg at 25°C
• Refractive Index: 1.665
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -1.23±0.10(Predicted)
• Sensitive: Light Sensitive
• BRN: 109100
• CAS DataBase Reference: 2-Bromo-5-iodopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-5-iodopyridine(73290-22-9)
• EPA Substance Registry System: 2-Bromo-5-iodopyridine(73290-22-9)

Safety Data

• Hazard Codes: Xn,Xi
• Statements: 22-37/38-41
• Safety Statements: 26-36/39
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 73290-22-9(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline

Uses

2-Bromo-5-iodopyridine can be used to develop fluorescent compounds (manisyl-substituted terpyridine, bipyridine, and phenanthroline). It is also a useful reagent for investigating the structure/activity relationships of non-nucleoside adenosine kinase inhibitors.

InChI:InChI=1/C5H3BrIN/c6-5-2-1-4(7)3-8-5/h1-3H

Upstream product

• 109-04-6 2-bromo-pyridine 
• 624-28-2 2,5-dibromopyridine 

Downstream Products

• 116195-81-4 2,5-di-iodopyridine 
• 338989-69-8 2-bromo-5-(4-dimethoxy-2,6-dimethylphenyl)pyridine 
• 50488-42-1 2-bromo-5-(trifluoromethyl)pyridine 
• 569672-53-3 2-bromo-5-({3-hexoxymethyl-5-[(triisopropylsilyl)ethynyl]phenyl}ethynyl)pyridine 
• 569672-28-2 2-bromo-5-ethynylpyridine 
• 569672-52-2 2-bromo-5-({3-hexoxy-5-[(triisopropylsilyl)ethynyl]phenyl}ethynyl)pyridine 
• 569672-54-4 2-bromo-5-({3-[(triisopropylsilyl)ethynyl]-5-(tetrahydropyran-2-yloxymethyl)phenyl}ethynyl)pyridine 
• 517895-32-8 2-bromo-5-{[3-hexoxy-5-({3-hexoxy-5-[(triisopropylsilyl)ethynyl]phenyl}ethynyl)phenyl]ethynyl}pyridine 
• 569672-41-9 2-bromo-5-{[3-hexoxymethyl-5-({3-(tetrahydropyran-2-yloxymethyl)-5-[(triisopropylsilyl)ethynyl]phenyl}ethynyl)phenyl]ethynyl}pyridine 
• 517895-34-0 2-bromo-5-{[3-hexoxymethyl-5-({3-hexoxymethyl-5-[(triisopropylsilyl)ethynyl]phenyl}ethynyl)phenyl]ethynyl}pyridine 
• 569672-48-6 2-bromo-5-[(3-hexoxymethyl-5-{[4-({3-hexoxymethyl-5-[(triisopropylsilyl)ethynyl]phenyl}ethynyl)phenyl]ethynyl}phenyl)ethynyl]pyridine 
• 87789-45-5 4-(5'-iodopyrid-2'-yloxy)phenyl tert.-butyl ether 
• 1220388-59-9 bis(2-bromo-5-pyridyl) selenide 
• 1227746-36-2 2-(6-bromopyridin-3-yl)-8a-methyl-3-p-tolylindolizin-1(8aH)-one 

Relevant articles and documents

Deprotonative metalation of chloro- and bromopyridines using amido-based bimetallic species and regioselectivity-computed CH acidity relationships

A series of chloro- and bromopyridines have been deprotometalated by using a range of 2,2,6,6-tetramethylpiperidino-based mixed lithium-metal combinations. Whereas lithium-zinc and lithium-cadmium bases afforded different mono- and diiodides after subsequent interception with iodine, complete regioselectivities were observed with the corresponding lithium-copper combination, as demonstrated by subsequent trapping with benzoyl chlorides. The obtained selectivities have been discussed in light of the CH acidities of the substrates, determined both in the gas phase and as a solution in THF by using the DFT B3LYP method.