73336-28-4

Basic information

• Product Name: 1,3-Cyclohexanedione, 2-(2-bromo-2-propenyl)-
• CAS NO: 73336-28-4
• Molecular Formula: C9H11BrO2
• Molecular Weight: 231.089
• Mol File: 73336-28-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3-Cyclohexanedione, 2-(2-bromo-2-propenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Cyclohexanedione, 2-(2-bromo-2-propenyl)-(73336-28-4)
• EPA Substance Registry System: 1,3-Cyclohexanedione, 2-(2-bromo-2-propenyl)-(73336-28-4)

Safety Data

• Hazardous Substances Data: 73336-28-4(Hazardous Substances Data)

Upstream product

• 504-02-9 1,3-cylohexanedione 
• 513-31-5 2-bromoallyl bromide 

Downstream Products

• 50615-16-2 2-methyl-6,7-dihydro-5H-benzofuran-4-one 
• 121287-08-9 2-(2-Bromo-allyl)-3-(3-isopropenyl-4-methyl-pent-3-enyl)-cyclohex-2-enone 
• 72211-20-2 2-methyl-1-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one 
• 35308-68-0 1,5,6,7-tetrahydro-2-methyl-4H-indol-4-one 
• 121287-06-7 2-(2-Bromo-allyl)-3-methoxy-cyclohex-2-enone 

Relevant articles and documents

Synthesis and structure-activity relationships of a series of substituted 2-(1H-furo[2,3-g]indazol-1-yl)ethylamine derivatives as 5-HT2C receptor agonists

A series of novel indazole derivatives were synthesized, and their structure-activity relationships examined in order to identify potent and selective 5-HT2C receptor agonists. Among these compounds, (S)-2-(7-ethyl-1H-furo[2,3-g]indazol-1-yl)-1-methylethylamine (YM348) had a good in vitro profile, that is, high agonistic activity to the human 5-HT2C receptor subtype (EC50 = 1.0 nM) and high selectivity over 5-HT2A receptors. This compound was also effective in a rat penile erection model when administered po.

SYNTHETIC EFFORTS DIRECTED TOWARDS THE TAXOL SKELETON. THE SATURATED C-RING APPROACH

The type 2 intramolecular Diels-Alder reaction is utilized to assemble a taxol precursor.