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736992-21-5

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736992-21-5 Usage

General Description

"D-Arginyl-2,6-diMethyl-L-tyrosyl-L-lysyl-L-phenylalaninamine" is a complex organic compound generally classified as a peptide. The name indicates the precise arrangement and types of amino acids (D-Arginine, L-tyrosine, L-lysine, L-phenylalanine) involved within the compound, with specific modifications such as methylation. Peptides are integral in various biological functions, acting as hormones, neurotransmitters, and pharmacological agents. This specific compounds' properties, uses, and implications may vary based on its structure, and are subjects to research in biochemical and medicinal fields. However, detailed information about this specific compound is limited due to its complexity and specific scientific usage.

Check Digit Verification of cas no

The CAS Registry Mumber 736992-21-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,3,6,9,9 and 2 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 736992-21:
(8*7)+(7*3)+(6*6)+(5*9)+(4*9)+(3*2)+(2*2)+(1*1)=205
205 % 10 = 5
So 736992-21-5 is a valid CAS Registry Number.

736992-21-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl]amino]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]hexanamide

1.2 Other means of identification

Product number -
Other names L-Phenylalaninamide,D-arginyl-2,6-dimethyl-L-tyrosyl-L-lysyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:736992-21-5 SDS

736992-21-5Downstream Products

736992-21-5Relevant articles and documents

A novel mitochondria-targeting tetrapeptide for subcellular delivery of nanoparticles

Sun, Yanhui,Zhan, Aiyan,Zhou, Shuang,Kuang, Xiao,Shen, Hongyan,Liu, Hongzhuo,Xu, Youjun

, p. 1435 - 1439 (2019)

Mitochondrial dysfunction is associated with the emergence of several neurological and cardiovascular diseases. Hence, mitochondria-targeting delivery strategies are highly significant and critically needed. In this study, we developed a small library of peptides simulating the mitochondria-targeting peptide SS-31, a promising tetra-peptide with antioxidant character, and subsequently evaluated the toxicity, antioxidant ability and mitochondrial delivery of nanoparticles. Among the designed peptides, RF-2 (D-Arg-Dmt-Arg-Phe-NH2) showed controlled toxicity and excellent protection against gentamicin-induced hair cell damage, as compared with SS-31. More importantly, RF-2-modified PLGA nanoparticles demonstrated high colocalization with mitochondria and comparable specific subcellular accumulation, when compared with SS-31. Taken together, the obtained results supported RF-2 as a mitochondria-targeting peptide with high potential as a targeted carrier.

TETRAPEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME

-

Paragraph 0093; 0094, (2016/10/04)

The present invention is to provide a method for the efficient production on an industrial scale of SS-31 (D-Arg-Dmt-Lys-Phe-NH2), which is an SS peptide. According to the present invention, the desired SS-31 is produced by efficiently synthesizing a tetrapeptide compound as a precursor of SS-31 and improving the tetrapeptide purity by crystallization.

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