7374-53-0

Basic information

• Product Name: PROPAZINE-2-HYDROXY
• Synonyms: PROPAZINE-2-HYDROXY;PROPAZIN-2-HYDROXY PESTANAL, 100 MG;propazine-2-hydroxy solution;HYDROXYPROPAZINE;2-Hydroxy-4,6-bis(isopropylamino)-1,3,5-triazine;2-Hydroxypropazine;2,4-Bis(isopropylamino)-1,3,5-triazine-6(5H)-one;4,6-Bis[(1-methylethyl)amino]-1,3,5-triazin-2(1H)-one
• CAS NO: 7374-53-0
• Molecular Formula: C9H17N5O
• Molecular Weight: 211.26
• EINECS: 200-659-6
• Mol File: 7374-53-0.mol
• Article Data: 2

Chemical Properties

• Melting Point: >300 °C
• Boiling Point: 400.6°C (rough estimate)
• Flash Point: 11 °C
• Appearance: /
• Density: 1.3222 (rough estimate)
• Vapor Pressure: 0.00282mmHg at 25°C
• Refractive Index: 1.7610 (estimate)
• Storage Temp.: APPROX 4°C
• PKA: 6.48±0.70(Predicted)
• Water Solubility: 102.9mg/L(2 oC)
• CAS DataBase Reference: PROPAZINE-2-HYDROXY(CAS DataBase Reference)
• NIST Chemistry Reference: PROPAZINE-2-HYDROXY(7374-53-0)
• EPA Substance Registry System: PROPAZINE-2-HYDROXY(7374-53-0)

Safety Data

• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45
• RIDADR: UN1230 3/PG 2
• Hazardous Substances Data: 7374-53-0(Hazardous Substances Data)

Usage

General Description

PROPAZINE-2-HYDROXY is a chemical compound that is used as an agricultural pesticide and herbicide. It is a derivative of the herbicide propazine and is commonly used to control the growth of unwanted plants in agricultural fields. PROPAZINE-2-HYDROXY is an effective tool for farmers to manage weed populations and optimize crop yields. It works by inhibiting the growth of specific enzymes in plants, leading to their eventual death. Despite its usefulness in agriculture, PROPAZINE-2-HYDROXY should be handled with care and according to safety guidelines to prevent any negative effects on human health and the environment.

InChI:InChI=1/C9H17N5O/c1-5(2)10-7-12-8(11-6(3)4)14-9(15)13-7/h5-6H,1-4H3,(H3,10,11,12,13,14,15)

Upstream product

• 7287-19-6 2-methylthio-4,6-bis(isopropylamino)-s-triazine 
• 247236-43-7 2,4-(N,N'-Diisopropyl)diamino-6-methanesulfonate ester 1,3,5-triazine 
• 55723-98-3 2,4-(N,N'-Diisopropyl)diamino-6-methylsulfonyl-1,3,5-triazine 

Relevant articles and documents

Identification of disinfection by-products of selected triazines in drinking water by LC-Q-ToF-MS/MS and evaluation of their toxicity

During the development of an on-line solid phase extraction-liquid chromatography-ultraviolet detection (SPE-LC-UV) analytical method for determination of eight selected triazines; ametryn, atrazine, cyanazine, metrybuzine, prometryn, propazin, simazine, and terbutryn, in drinking water, it was observed that the retention times of three of them (ametryn, prometryn, and terbutryn) in Milli-Q water were different from those in chlorinated Milli-Q water, indicating the formation of new products. The cause of this change was found in the oxidation of the molecules as a result of chlorination with sodium hypochlorite. Experiments performed at varying concentrations of triazines and hypochlorite showed that the extent of the reaction depended on their relative concentrations. At the maximum admissible level of 100 ng/l for individual pesticides in drinking water, no apparent transformation was observed in the absence or at low concentrations (0.05 mg/l) of hypochlorite; however, on increasing the concentration of hypochlorite to the level typically present in drinking water (0.9 mg/l) the transformation was complete. The reaction is quite fast; within 1 h the parent compound is completely degraded and after 22 h the concentrations of the by-products are constant. Investigation of the by-products by ultra performance liquid chromatography-quadrupole-time of flight- tandem mass spectrometry (UPLC-Q-ToF-MS/MS) has shown that all three triazines follow a similar transformation pathway, forming four new molecules whose structure have been elucidated. The acute toxicity of the new products was investigated using a standard method based on the bioluminescence inhibition of Vibrio fischeri, and the by-products showed a higher toxicity than that of the parent compounds. Copyright