73799-64-1

Basic information

• Product Name: 3-Azabicyclo[3.1.0]hexane hydrochloride
• Synonyms: 3-Azabicyclo[3.1.0]hexane hydrochloride;3-Azabicyclo[3.1.]hexane hydrochloride;3-Azabicyclo[3.1.0]hexane HCl; 73799-64-1
• CAS NO: 73799-64-1
• Molecular Formula: C5H10ClN
• Molecular Weight: 119.5926
• Product Categories: fine chemicals
• Mol File: 73799-64-1.mol

Chemical Properties

• Boiling Point: 156.4°C at 760 mmHg
• Flash Point: 48.4°C
• Appearance: /
• Vapor Pressure: 2.55mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 3-Azabicyclo[3.1.0]hexane hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Azabicyclo[3.1.0]hexane hydrochloride(73799-64-1)
• EPA Substance Registry System: 3-Azabicyclo[3.1.0]hexane hydrochloride(73799-64-1)

Safety Data

• Hazardous Substances Data: 73799-64-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Azabicyclo[3.1.0]hexane hydrochloride is used as a synthetic intermediate for the production of derivatives of Tolterodine and Oxybutynin. These derivatives are employed in the treatment of urinary incontinence, a condition characterized by the involuntary leakage of urine. The use of restricted azabicyclics in these derivatives allows for the replacement of open chain amines, which can improve the overall efficacy and safety of the final drug product.
Additionally, 3-Azabicyclo[3.1.0]hexane hydrochloride is used in the derivation and preparation of dipeptidyl peptidase-IV (DPP-IV) inhibitors. DPP-IV inhibitors are a class of drugs that help regulate blood sugar levels and are commonly used in the treatment of type 2 diabetes. By acting as a synthetic intermediate, 3-Azabicyclo[3.1.0]hexane hydrochloride plays a crucial role in the development of these life-saving medications.

InChI:InChI=1/C5H9N.ClH/c1-4-2-6-3-5(1)4;/h4-6H,1-3H2;1H