74058-68-7

Basic information

• Product Name: 2-Thioxo-3-thiazolidinecarboxylic acid benzyl ester
• Synonyms: 2-Thioxo-3-thiazolidinecarboxylic acid benzyl ester;3-Thiazolidinecarboxylic acid, 2-thioxo-, phenylMethyl ester
• CAS NO: 74058-68-7
• Molecular Formula: C₁₁H₁₁NO₂S₂
• Molecular Weight: 253.34054
• Product Categories: chemical additive;pharmaceutical intermediate;Heterocycles;Metabolites & Impurities;Sulfur & Selenium Compounds
• Mol File: 74058-68-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.38
• Solubility: Dichloromethane, Ethyl Acetate
• CAS DataBase Reference: 2-Thioxo-3-thiazolidinecarboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thioxo-3-thiazolidinecarboxylic acid benzyl ester(74058-68-7)
• EPA Substance Registry System: 2-Thioxo-3-thiazolidinecarboxylic acid benzyl ester(74058-68-7)

Safety Data

• Hazardous Substances Data: 74058-68-7(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 74058-68-7 differently. You can refer to the following data:
1. thiazolidin e thione pharmaceutical intermediate
2. Intermediate in the preparation of alkoxycarbonylthiazolethione derivatives.

Upstream product

• 96-53-7 2-mercaptothiazoline 
• 501-53-1 benzyl chloroformate 
• 134469-06-0 thiazolidine-2-thione 
• 63987-96-2 thallium salt of Δ²-1,3-thiazoline-2-thiol 

Downstream Products

• 122248-80-0 benzyl N-[3-[(3-aminopropyl)amino]propyl]carbamate 
• 89965-57-1 (4S,5R)-N-<3-(benzyloxycarbonylamino)propyl>-N-<4-(benzyloxycarbonylamino)butyl>-2-(2-hydroxyphenyl)-5-methyl-4,5-dihydro-oxazole-4-carboxamide 
• 171019-90-2 <3--16-<(tetrahydro-2H-pyran-2-yl)oxy>hexadecanamide>propyl>carbamic acid, dibenzyl ester 
• 171019-91-3 <3--16-hydroxyhexadecanamide>propyl>carbamic acid, dibenzyl ester 
• 74058-75-6 N^α-(benzyloxycarbonyl)histamine 
• 14997-58-1 N-[(benzyloxy)carbonyl]-L-histidine 
• 136113-05-8 (3aS,4R,6R,7R,7aR)-7-Hydroxy-4-hydroxymethyl-6-methoxy-tetrahydro-[1,3]dioxolo[4,5-c]pyran-2-one 
• 127867-58-7 methyl α-D-glucopyranoside benzyl carbonate 
• 50710-77-5 methyl 2,3-O-carbonyl-α-D-mannopyranoside 
• 136113-02-5 Carbonic acid benzyl ester (2R,3S,4S,5S,6S)-3,4,5-trihydroxy-6-methoxy-tetrahydro-pyran-2-ylmethyl ester 
• 39896-97-4 benzyl-carbamic acid benzyl ester 
• 24498-31-5 (S)-methyl 2-amino-6-(benzyloxycarbonylamino)hexanoate 
• 15545-10-5 Z-His-OMe 
• 89965-56-0 <3-<<4-(carboxyamino)butyl>amino>propyl>carbamic acid, dibenzyl ester 

Relevant articles and documents

Acylated amine compounds which are useful fungicigal agents

A compound selected from the group consisting of a compound of the formula STR1 wherein R1 is selected from the group consisting of Ar-O- and aryl, polyaryl and condensed polyaryl unsubstituted or substituted and heterocycle unsubstituted or substituted, Ar is aryl of 6 to 14 carbon atoms unsubstituted or substituted, heteroaryl unsubstituted or substituted and heterocyclic unsubstituted or substituted, W is selected from the group comsisting of --(CH2)n1 --or --(CH2)n2 --NY--(CH2)n3, n1, n2 and n3 are individually integers from 2 to 6, Y is selected from the group consisting of hydrogen, alkyl of 1 to 12 carbon atoms, aryl of 6 to 12 carbon atoms and aralkyl of 7 to 14 carbon atoms unsubstituted or substituted, --COOAlk and --COR2, Alk is alkyl of 1 to 12 carbon atoms, R2 is selected from the group consisting of alkyl of 1 to 12 carbon atoms, alkenyl and alkynyl of 2 to 12 carbon atoms, aryl of 6 to 14 carbon atoms, aralkyl of 7 to 18 carbon atoms unsubstituted or substituted and heterocyclic unsubstituted or substituted, Z is selected from the group consisting of hydrogen, STR2 R2 is alkyl of 1 to 12 carbon atoms or aralkyl of 7 to 18 carbon atoms, Alk' is alkyl of 1 to 12 carbon atoms, ArAlk is aralkyl of 7 to 18 carbon atoms, R2 ' is R2, R3 and R3 ' are selected from the group consisting of aryl substituted or unsubstituted, heteroaryl substituted or unsubstituted, heterocyclic unsubstituted or substituted and R1 with the proviso that Z is not hydrogen when W is --(CH2)3 --and R1 is 2,4-dichlorophenoxy and their non-toxic, pharmaceutically acceptable acid addition salts having fungicidal activity.

Studies on the Sructure of Some Derivatives of 1,3-Thiazolidine-2-thione and Δ2-1,3-Thiazoline-2-thiol

Two types of reactions have been observed for the ambident anion of 1,3-thiazolidine-2-thione: regioselective N-acylation and S-alkylation.The structures of the products, amides and thioethers, were determined by X-ray crystallographic analysis and by ass

MONITORED AMINOLYSIS OF 3-ACYLTHIAZOLIDINE-2-THIONE : A NEW CONVENIENT SYNTHESIS OF AMIDE

3-Acylthiazolidine-2-thiones (1) were easily prepared and they were treated with several amines in dichloromethane to give amides 4 in very high yields within a short time.Aminoalcohols and aminophenols were selectively converted into acylaminoalcohols and acylaminophenols, respectively, by this reaction.One can monitor the reaction by disappearance of the yellow color of the starting material 1.Some amide alkaloids (15-18) have effectively been synthesized.