7421-76-3

Basic information

• Product Name: Indane-1,3-dione, 2-(4-methoxybenzylideno)-
• Synonyms: Indane-1,3-dione, 2-(4-methoxybenzylideno)-;2-(4-methoxybenzylidene)-1H-indene-1,3(2H)-dione
• CAS NO: 7421-76-3
• Molecular Formula: C₁₇H₁₂O₃
• Molecular Weight: 264.27538
• Mol File: 7421-76-3.mol
• Article Data: 39

Chemical Properties

• Melting Point: 155-156 °C
• Boiling Point: 479.2±45.0 °C(Predicted)
• Appearance: /
• Density: 1.299±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Indane-1,3-dione, 2-(4-methoxybenzylideno)-(CAS DataBase Reference)
• NIST Chemistry Reference: Indane-1,3-dione, 2-(4-methoxybenzylideno)-(7421-76-3)
• EPA Substance Registry System: Indane-1,3-dione, 2-(4-methoxybenzylideno)-(7421-76-3)

Safety Data

• Hazardous Substances Data: 7421-76-3(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 606-23-5 1H-indene-1,3(2H)-dione 
• 123-11-5 4-methoxy-benzaldehyde 
• 836-41-9 p-methoxybenzylidene-phenylamine 
• 5428-32-0 N,N'-bis(4-methoxybenzylidene)ethylenediamine 
• 3246-78-4 N-(4-methoxybenzylidene)-4-methylaniline 
• 3457-77-0 1,3-dioxo-indan-2-carboxylic acid ethyl ester 
• 1896-62-4 (E)-benzalacetone 
• 84-66-2 Diethyl phthalate 
• 49546-71-6 5-(4-methoxybenzylidene)barbituric acid 
• 964-29-4 2-(4-methoxybenzyl)indane-1,3-dione 

Downstream Products

• 84354-03-0 2-methoxycarbonyl-2-(4-methoxyphenyl)-indan-1,3-dione 
• 122631-53-2 2-[Diethylamino-(4-methoxy-phenyl)-methyl]-indan-1,3-dione 
• 82607-16-7 4-(4-Methoxy-phenyl)-1H-indeno[1,2-b]pyridine-2,5-dione 
• 204988-85-2 4-(4-Methoxy-phenyl)-5-oxo-2-thioxo-2,5-dihydro-1H-indeno[1,2-b]pyridine-3-carbonitrile 
• 1610342-19-2 C₂₂H₂₀O₅ 
• 19294-99-6 2,6-bis(4-methoxyphenyl)spiro[cyclohexane-1,2'-indan]-1',3',4-trione 

Relevant articles and documents

In vitro anti-melanogenic effects of chimeric compounds, 2-(substituted benzylidene)-1,3-indanedione derivatives with a β-phenyl-α, β -unsaturated dicarbonyl scaffold

Tyrosinase is considered a key contributor to melanogenesis, and safe, potent tyrosinase inhibitors are needed for medical and cosmetic purposes to treat skin hyperpigmentation and prevent fruit and vegetable browning. According to our accumulated SAR dat

Synthesis of novel spiro-tetrahydroquinoline derivatives and evaluation of their pharmacological effects on wound healing

A highly diastereoselective method for the synthesis of novel spiro-tetrahydroquinoline derivatives is reported here, using a one-pot reaction method. All compounds were characterized by1 H-nuclear magnetic resonance (NMR) and mass spectroscopy

Highly diastereoselective spiro-cyclopropanation of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides

A highly diastereoselective spiro-cyclopropanation reaction of 2-arylidene-1,3-indanediones and dimethylsulfonium ylides has been developedviabase-induced annulation. This efficient and simple protocol features simple operations, mild conditions and excellent functional group compatibility. A variety of structurally interesting spiro-cyclopropanes were prepared in excellent yields and diastereomeric ratios (up to 97% yield and 20?:?1 dr). Also, ring expansion of the cyclopropanation product to quickly deliver a complex indeno[1,2-c]pyridazine structure showcased an interesting application of this method.