74308-31-9Relevant articles and documents
Quinazoline substituted 1, 2, 3-triazole derivative as well as pharmaceutical composition, preparation method and application thereof
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Paragraph 0068-0072, (2022/03/31)
The invention discloses a quinazoline substituted 1, 2, 3-triazole derivative, the derivative is shown as a general formula (I), and the definition of each substituent group is shown in the specification. In addition, the invention also discloses a preparation method of the compound. The compound shown in the general formula (I) has an inhibiting effect on proliferation of tumor cells, also has an inhibiting effect on proliferation of human colon cancer (HCT-116) and human lung cancer cell strain (A549) cells, and can be used as an antitumor drug.
A reliable one-pot synthesis of aryl azides from aryl amines using organotin azides as effective and recoverable reagents
Godoy Prieto, Leonela,Lo Fiego, Marcos J.,Chopa, Alicia B.,Lockhart, María T.
supporting information, p. 26 - 32 (2016/12/18)
A mild and mass-efficient procedure based on the one-pot diazotization-azidodediazoniation of aromatic amines is described. A wide range of aryl azides are obtained in moderate to high yields by using tributyltin azide as an effective and reusable azide source in the presence of p-toluenesulfonic acid at room temperature. The method was also successfully applied employing an insoluble polymer-supported organotin azide.
Nitrogen functionalities in palladium-catalyzed reactions on solid supports: A case study
Knepper, Kerstin,Vanderheiden, Sylvia,Braese, Stefan
, p. 1886 - 1898 (2007/10/03)
Three different Palladium-catalyzed reactions (Heck, Suzuki, Sonogashira) were carried out on three different types of linkers on solid supports. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.