Welcome to LookChem.com Sign In|Join Free

Cas Database

74317-85-4

74317-85-4

Identification

  • Product Name:Benzoicacid, 2-bromo-4-methoxy-

  • CAS Number: 74317-85-4

  • EINECS:214-589-6

  • Molecular Weight:231.046

  • Molecular Formula: C8H7BrO3

  • HS Code:

  • Mol File:74317-85-4.mol

Synonyms:p-Anisicacid, 2-bromo- (6CI);2-Bromo-4-methoxybenzoic acid;

Post Buying Request Now
Entrust LookChem procurement to find high-quality suppliers faster

Safety information and MSDS view more

  • Signal Word:no data available

  • Hazard Statement:no data available

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price

  • Manufacture/Brand
  • Product Description
  • Packaging
  • Price
  • Delivery
  • Purchase
  • Manufacture/Brand:TRC
  • Product Description:2-Bromo-4-methoxybenzoicacid
  • Packaging:100mg
  • Price:$ 45
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:TRC
  • Product Description:2-Bromo-4-methoxybenzoicacid
  • Packaging:250mg
  • Price:$ 50
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:2-Bromo-4-methoxybenzoic acid
  • Packaging:5 g
  • Price:$ 48
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:2-Bromo-4-methoxybenzoic acid
  • Packaging:1 g
  • Price:$ 16
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:2-Bromo-4-methoxybenzoic acid
  • Packaging:25 g
  • Price:$ 167
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Medical Isotopes, Inc.
  • Product Description:2-Bromo-4-methoxybenzoicacid 95+%
  • Packaging:1 g
  • Price:$ 350
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:2-Bromo-4-methoxybenzoic acid
  • Packaging:1g
  • Price:$ 156
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Matrix Scientific
  • Product Description:2-Bromo-4-methoxybenzoic acid
  • Packaging:5g
  • Price:$ 594
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Crysdot
  • Product Description:2-Bromo-4-methoxybenzoicacid 98%
  • Packaging:100g
  • Price:$ 386
  • Delivery:In stock
  • Buy Now
  • Manufacture/Brand:Chemcia Scientific
  • Product Description:2-Bromo-4-methoxy-benzoicacid 95%
  • Packaging:100 G
  • Price:$ 375
  • Delivery:In stock
  • Buy Now

Relevant articles and documentsAll total 14 Articles be found

Photoinduced Carbon Tetrabromide Initiated Aerobic Oxidation of Substituted Toluenes to Carboxylic Acids

Li, Xiaoqing,Xu, Xiangsheng,Yan, Xiaoyu,Yan, Xinhuan,Zhang, Guofu,Zheng, Kun

, p. 272 - 274 (2020/02/18)

A mild and metal-free procedure is reported for the aerobic oxidation of substituted toluenes to carboxylic acids by using CBr 4 as initiator under irradiation from a 400 nm blue light-emitting diode.

Synthesis method of benzoic acid compounds

-

Paragraph 0146; 0147; 0148; 0149, (2019/12/25)

The invention discloses a photocatalytic oxidation synthesis method of benzoic acid compounds, and the photocatalytic oxidation synthesis method comprises the following specific steps: mixing and dissolving toluene compounds and a catalyst in a solvent, reacting for 24-60h in the presence of an oxidant under the conditions of 350-460 nm LED illumination and a temperature of 20-80 DEG C, and performing post-treatment on the reaction liquid to obtain the benzoic acid compounds. The photocatalytic oxidation synthesis method has the advantages of no need of metal catalysts, simple operation and mild reaction conditions; oxygen is used as an oxidant, and the photocatalytic oxidation synthesis method has high atom economy, cheap reagent and environmental protection. The photocatalytic oxidationsynthesis method has good substrate applicability, and various substituents can realize the synthesis of corresponding benzoic acid compounds.

METHOD FOR PRODUCING 2-HALOGENATED BENZOIC ACIDS

-

Paragraph 0064, (2018/04/20)

The purpose of the present invention is to provide a method for producing 2-halogenated benzoic acids, the method imparting high regioselectivity (high selectivity) and having a shorter reaction time than does the conventional reaction. This method for producing 2-halogenated benzoic acids, in order to achieve the above purpose, is characterized in that benzoic acids and a halogenating agent are reacted in the presence of an alkaline compound, making it possible to highly selectively obtain 2-halogenated benzoic acids.

Zn-Catalyzed Enantio- and Diastereoselective Formal [4 + 2] Cycloaddition Involving Two Electron-Deficient Partners: Asymmetric Synthesis of Piperidines from 1-Azadienes and Nitro-Alkenes

Chu, John C. K.,Dalton, Derek M.,Rovis, Tomislav

supporting information, p. 4445 - 4452 (2015/04/14)

We report a catalytic asymmetric synthesis of piperidines through [4 + 2] cycloaddition of 1-azadienes and nitro-alkenes. The reaction uses earth abundant Zn as catalyst and is highly diastereo- and regioselective. A novel BOPA ligand (F-BOPA) confers high reactivity and enantioselectivity in the process. The presence of ortho substitution on the arenes adjacent to the bis(oxazolines) was found to be particularly impactful, due to limiting the undesired coordination of 1-azadiene to the Lewis acid and thus allowing the reaction to be carried out at lower temperature. A series of secondary kinetic isotope effect studies using a range of ligands implicates a stepwise mechanism for the transformation, involving an initial Michael-type addition of the imine to the nitro-alkene followed by a cyclization event. The stepwise mechanism obviates the electronic requirement inherent to a concerted mechanism, explaining the successful cycloaddition between two electron-deficient partners. (Chemical Equation Presented).

ENHANCING AUTOPHAGY OR INCREASING LONGEVITY BY ADMINISTRATION OF UROLITHINS OR PRECURSORS THEREOF

-

Sheet 30, (2014/01/17)

Disclosed are methods, compounds, and compositions useful for increasing autophagy and promoting longevity. The methods, compounds, and compositions relate to urolithins and urolithin precursors and use thereof. Certain urolithins are represented by Formula I, while certain urolithin precursors are represented by Formula IV. The urolithin may be urolithin A, urolithin B, urolithin C, or urolithin D. The urolithin precursor may be ellagic acid or an ellagitannin. The methods include in vivo, ex vivo, and in vitro uses of the compounds and compositions.

Process route upstream and downstream products

Process route

4-methoxybenzoic acid
100-09-4

4-methoxybenzoic acid

3-bromo-4-methoxybenzoic acid
99-58-1

3-bromo-4-methoxybenzoic acid

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
With 1,2-dibromo-1,1,2,2-tetrachloroethane; N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; at -78 - 20 ℃; Title compound not separated from byproducts.;
3-bromo-4-methylanisole
36942-56-0

3-bromo-4-methylanisole

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
With carbon tetrabromide; oxygen; In acetonitrile; at 20 ℃; for 60h; Irradiation;
79%
With carbon tetrabromide; oxygen; In acetonitrile; at 20 ℃; for 60h; UV-irradiation;
78.5%
With alkaline permanganate;
With potassium permanganate;
1-(2-bromo-4-methoxyphenyl)ethanone
89691-67-8

1-(2-bromo-4-methoxyphenyl)ethanone

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
With sodium hydroxide; bromine; at 35 - 38 ℃; for 24h;
92%
With sodium hydroxide; bromine; In water; at 35 - 38 ℃; for 24h;
92%
With sodium hypobromide; water; sodium hydroxide; at 36 ℃; for 24h;
71%
1-(2-bromo-4-methoxyphenyl)ethanone; With bromine; sodium hydroxide; at 0 - 36 ℃;
With hydrogenchloride; In water;
68%
With sodium hydroxide; bromine; In water; at 70 ℃;
50%
With sodium hydroxide; bromine;
Multi-step reaction with 2 steps
1: sodium t-butanolate / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
2: Oxone; sodium hydrogencarbonate / water; acetone / 2 h / 0 °C
With Oxone; sodium hydrogencarbonate; sodium t-butanolate; In tetrahydrofuran; water; acetone;
(2-bromo-4-methoxyphenyl)phenylmethanone
59142-57-3

(2-bromo-4-methoxyphenyl)phenylmethanone

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
(2-bromo-4-methoxyphenyl)phenylmethanone; With sodium hydroxide; In water; at 0 ℃; for 15h;
With hydrogenchloride; In water;
95%
4-methoxybenzoic acid
100-09-4

4-methoxybenzoic acid

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
4-methoxybenzoic acid; With bromine; sodium hydroxide; In water; at 0 - 5 ℃; for 1h;
With hydrogenchloride; sodium sulfite; In water; toluene; at 70 ℃; for 1h;
91.4%
4-methoxyanthranilic acid
4294-95-5

4-methoxyanthranilic acid

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
4-methoxyanthranilic acid; With hydrogen bromide; acetic acid; sodium nitrite; In water; at 0 ℃; Inert atmosphere;
With copper(I) bromide; In water; at 0 - 65 ℃; Inert atmosphere;
90%
2-bromo-4-methoxybenzoic acid ethyl ester
1208075-63-1

2-bromo-4-methoxybenzoic acid ethyl ester

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
With Oxone; sodium hydrogencarbonate; In water; acetone; at 0 ℃; for 2h;
77%
3-methoxyphenyl bromide
2398-37-0

3-methoxyphenyl bromide

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
Multi-step reaction with 2 steps
1: 59 percent / AlCl3
2: Br2; NaOH
With sodium hydroxide; aluminium trichloride; bromine; 1: Friedel-Crafts acylation;
Multi-step reaction with 2 steps
1: 59 percent / AlCl3 / CH2Cl2 / 20 °C
2: 92 percent / bromine; NaOH / 24 h / 35 - 38 °C
With sodium hydroxide; aluminium trichloride; bromine; In dichloromethane;
Multi-step reaction with 3 steps
1: zirconium(IV) chloride / dichloromethane / 1 h / -10 - 20 °C / Inert atmosphere
2: sodium t-butanolate / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
3: Oxone; sodium hydrogencarbonate / water; acetone / 2 h / 0 °C
With Oxone; zirconium(IV) chloride; sodium hydrogencarbonate; sodium t-butanolate; In tetrahydrofuran; dichloromethane; water; acetone;
Multi-step reaction with 2 steps
1: aluminum (III) chloride / dichloromethane / 2 h / 0 - 20 °C
2: sodium hypobromide; sodium hydroxide; water / 24 h / 36 °C
With aluminum (III) chloride; sodium hypobromide; water; sodium hydroxide; In dichloromethane; 1: |Friedel-Crafts Acylation;
2-bromo-4-methoxybenzoic acid methyl ester
17100-65-1

2-bromo-4-methoxybenzoic acid methyl ester

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃;
2-bromo-4-methoxybenzaldehyde
43192-31-0

2-bromo-4-methoxybenzaldehyde

2-bromo-4-methoxybenzoic acid
74317-85-4

2-bromo-4-methoxybenzoic acid

Conditions
Conditions Yield
With alkaline permanganate;

Global suppliers and manufacturers

Global( 48) Suppliers
  • Company Name
  • Business Type
  • Contact Tel
  • Emails
  • Main Products
  • Country
  • Amadis Chemical Co., Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:86-571-89925085
  • Emails:sales@amadischem.com
  • Main Products:29
  • Country:China (Mainland)
  • Shaanxi BLOOM TECH Co.,Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-29-86470566
  • Emails:sales@bloomtechz.com
  • Main Products:80
  • Country:China (Mainland)
  • Career Henan Chemical Co
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-371-86658258
  • Emails:purchase@coreychem.com
  • Main Products:137
  • Country:China (Mainland)
  • Win-Win chemical Co.Ltd
  • Business Type:Lab/Research institutions
  • Contact Tel:0086-577-64498589
  • Emails:sales@win-winchemical.com
  • Main Products:55
  • Country:China (Mainland)
  • GIHI CHEMICALS CO.,LIMITED
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-571-86217390
  • Emails:info@gihichem.com
  • Main Products:66
  • Country:China (Mainland)
  • Kono Chem Co.,Ltd
  • Business Type:Other
  • Contact Tel:86-29-86107037-8015
  • Emails:info@konochemical.com
  • Main Products:83
  • Country:China (Mainland)
  • Hangzhou Dingyan Chem Co., Ltd
  • Business Type:Manufacturers
  • Contact Tel:86-571-86465881,86-571-87157530,86-571-88025800
  • Emails:sales@dingyanchem.com
  • Main Products:95
  • Country:China (Mainland)
  • Finetech Industry Limited
  • Business Type:Trading Company
  • Contact Tel:86-27-87465837
  • Emails:sales@finetechnology-ind.com
  • Main Products:29
  • Country:China (Mainland)
  • Antimex Chemical Limied
  • Business Type:Lab/Research institutions
  • Contact Tel:0086-21-50563169
  • Emails:anthony@antimex.com
  • Main Products:163
  • Country:China (Mainland)
  • Hangzhou Ocean Chemical Co., Ltd.
  • Business Type:Lab/Research institutions
  • Contact Tel:+86-571-88025872, 28272092, 28272096
  • Emails:christina1618@hotmail.com
  • Main Products:70
  • Country:China (Mainland)
close
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 74317-85-4
Post Buying Request Now
close
Remarks: The blank with*must be completed