74646-37-0Relevant articles and documents
Gold-Catalyzed Tandem Oxidative Coupling Reaction between β-Ketoallenes and Electron-Rich Arenes to 2-Furylmethylarenes
Yasukawa, Naoki,Yamada, Yutaro,Furugen, Chikara,Miki, Yuya,Sajiki, Hironao,Sawama, Yoshinari
supporting information, p. 5891 - 5895 (2021/08/18)
A tandem oxidative coupling reaction of β-ketoallenes and arenes was developed, which leads to the formation of 2-furylmethylarenes using AuCl3 and phenyliodine diacetate. The AuIII salt catalyzed the cyclization of β-ketoallenes to form a 2-furylmethyl gold intermediate, and the subsequent C-H functionalization of arenes proceeded smoothly. During the oxidative coupling, nucleophilic additions occurred at the center and terminal carbon atoms of the allene moiety to form C-O and C-C bonds.
A practical procedure of propargylation of aldehydes
Ghosh, Papiya,Chattopadhyay, Angshuman
, p. 5202 - 5205 (2012/11/06)
An operationally simple procedure of propargylation of aldehydes in moist solvent (distilled THF) has been developed through direct addition of propargyl bromide to aldehyde substrates mediated with low valent iron or tin. The metals were spontaneously pr
Efficient propargylation of aldehydes and ketones catalyzed by titanocene(III)
Justicia, Jose,Sancho-Sanz, Iris,Alvarez-Manzaneda, Enrique,Oltra, J. Enrique,Cuerva, Juan M.
experimental part, p. 2295 - 2300 (2009/12/27)
We describe a novel method for the propargylation of a wide range of aldehydes and ketones catalyzed by titanocene(III) complexes under mild reaction conditions and compatible with many functional groups. Homopropargylic alcohols are obtained as the sole products even when ketones are used as starting materials, which is unusual in Barbier-type propargylations.
