75532-26-2

Basic information

• Product Name: C₁₀H₈O₄S
• Synonyms: C₁₀H₈O₄S
• CAS NO: 75532-26-2
• Molecular Weight: 224.237
• Mol File: 75532-26-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: C₁₀H₈O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀H₈O₄S(75532-26-2)
• EPA Substance Registry System: C₁₀H₈O₄S(75532-26-2)

Safety Data

• Hazardous Substances Data: 75532-26-2(Hazardous Substances Data)

Upstream product

• 110-00-9 furan 
• 75532-25-1 2,2,4,4-tetrahydrothiophene-3,4-dicarboxylic acid anhydride 

Downstream Products

• 110-00-9 furan 
• 75532-25-1 2,2,4,4-tetrahydrothiophene-3,4-dicarboxylic acid anhydride 
• 56-25-7 cantharidin 

Relevant articles and documents

The novel method to synthesis of cantharidin intermediate

Sulfur-containing dehydrocantharidin(SD) was yielded (76% to 96%) by Diels-Alder reaction in an ionic-liquid system under ordinary pressure and temperature. We explored the influences of different ionic-liquid types, reaction temperatures, and reaction times in this reaction. We found that the optimal reaction temperature was about 35°C, the reaction time was 20 h, and the most suitable ionic liquid was 1-butyl-3-methylimidazolium tetrafluoroborate. Furthermore, in the recycling process of ionic liquid, we found that CH3CN was the most suitable extraction solvent. We explored four steps in the synthetic route to SD and achieved a good yield of 38% in total. We envisage that this process could be further developed at an industrial scale for the synthesis of Cantharidin and is destined to be an environmentally friendly way to solve the lack of cantharis as a natural resource.

COMMERCIALLY VIABLE SYNTHESIS OF CANTHARIDIN AND BIOACTIVE CANTHARIDIN DERIVATIVES

The present disclosure provides methods for synthesizing cantharidin and cantharidin derivatives.

Total synthesis of (-)-palasonin and (+)-palasonin and related chemistry

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