76240-27-2

Basic information

• Product Name: 4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-HYDROXY-
• Synonyms: 4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-HYDROXY-;7-hydroxy-2,3-dihydro-4H-chromen-4-one;4H-1-Benzopyran-4-one,2,3-dihydro-7-hydroxy-(9CI);7-hydroxy-3,4-dihydro-2H-1-benzopyran-4-one;7-hydroxy-2,3-dihydrochroMen-4-one;2,3-Dihydro-7-hydroxy-4H-1-Benzopyran-4-one;7-HydroxychroMan-4-one;2,3-Dihydro-7-Hydroxy-4H-1-Benzopyran-4-One(WX645088)
• CAS NO: 76240-27-2
• Molecular Formula: C₉H₈O₃
• Molecular Weight: 164.15802
• Mol File: 76240-27-2.mol
• Article Data: 59

Chemical Properties

• Melting Point: 149 °C(Solv: water (7732-18-5))
• Boiling Point: 372.373°C at 760 mmHg
• Flash Point: 159.055°C
• Appearance: /
• Density: 1.343g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.604
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 7.75±0.20(Predicted)
• CAS DataBase Reference: 4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-HYDROXY-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-HYDROXY-(76240-27-2)
• EPA Substance Registry System: 4H-1-BENZOPYRAN-4-ONE, 2,3-DIHYDRO-7-HYDROXY-(76240-27-2)

Safety Data

• Hazardous Substances Data: 76240-27-2(Hazardous Substances Data)

Usage

General Description

4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy- is a chemical compound more commonly recognized under its simpler name of 7-Hydroxycoumarin. This organic substance belongs to the coumarins and coumarin derivatives family. It's often used as a photosensitizer due to its ability to absorb light, making it useful in adhesives, sealants, coatings, and other light-sensitive materials. It displays fluorescent properties, releasing a blue glow when exposed to ultraviolet light which is why it is also utilized in the creation of organic dyes. Though more research is needed, some studies suggest it might have some pharmacological properties such as antioxidant and antibacterial. Its safety for humans in large quantities is not entirely known.

InChI:InChI=1/C9H8O3/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-2,5,10H,3-4H2

Upstream product

• 42327-52-6 7-methoxy-chroman-4-one 
• 76240-23-8 3-(3-Hydroxyphenoxy)propanenitrile 
• 150-19-6 O-methylresorcine 
• 29682-12-0 1-[4-(benzyloxy)-2-hydroxyphenyl]ethanone 
• 108-46-3 recorcinol 
• 107-94-8 chloropropionic acid 
• 90721-47-4 3-(3-hydroxyphenoxy)propanoic acid 
• 625-36-5 2-chloropropionyl chloride 
• 105174-44-5 3-bromo-1-(2,4-dihydroxyphenyl)propan-1-one 
• 445408-54-8 7-acetoxy-chroman-4-one 
• 7623-09-8 2-chloropropionyl chloride 
• 860189-36-2 4-(4-benzyloxy-2-hydroxy-phenyl)-2,4-dioxo-butyric acid ethyl ester 
• 6345-73-9 7-benzyloxy-4-oxo-4H-chromene-2-carboxylic acid ethyl ester 
• 30113-83-8 7-hydroxy-4-oxo-4H-chromene-2-carboxylic acid 

Downstream Products

• 31042-20-3 7-(benzyloxy)chroman-4-one 
• 83162-84-9 Bonducellin 
• 111254-31-0 (E)-3-(4-hydroxy-3-methoxybenzylidene)-7-hydroxychroman-4-one 
• 104778-14-5 Sappanone A 
• 57052-72-9 2,3-Dihydro-7-hydroxy-4H-1-benzopyran 
• 118975-25-0 7-acetoxy-2,3-dihydro-3-(4-methoxybenzylidene)-1-benzopyran-4-one 
• 853760-23-3 7-{4-[3-hydroxy-2-methyl-4-(3-methylbutanoyl)phenoxy]butoxy}-2,3-dihydro-4H-chromen-4-one 
• 110064-50-1 3'-deoxy-sappanone A 
• 793724-32-0 (E)-7-hydroxy-3-(2',4'-dimethoxybenzylidene)chroman-4-one 
• 610778-85-3 (Z)-7-hydroxy-3-(4'-methoxybenzylidene)chroman-4-one 
• 854716-73-7 (E)-7-(7-bromoheptyloxy)-3-(3,4,5-trimethoxybenzylidene)chroman-4-one 
• 854716-76-0 (E)-7-{7-[(3-hydroxybenzyl)methylamino]heptyloxy}-3-(3,4,5-trimethoxybenzylidene)chroman-4-one 
• 171721-14-5 7-Benzyloxy-3,3-dibromo-chroman-4-one 

Relevant articles and documents

Visible light mediated selective oxidation of alcohols and oxidative dehydrogenation of N-heterocycles using scalable and reusable La-doped NiWO4nanoparticles

Visible light-mediated selective and efficient oxidation of various primary/secondary benzyl alcohols to aldehydes/ketones and oxidative dehydrogenation (ODH) of partially saturated heterocycles using a scalable and reusable heterogeneous photoredox catalyst in aqueous medium are described. A systematic study led to a selective synthesis of aldehydes under an argon atmosphere while the ODH of partially saturated heterocycles under an oxygen atmosphere resulted in very good to excellent yields. The methodology is atom economical and exhibits excellent tolerance towards various functional groups, and broad substrate scope. Furthermore, a one-pot procedure was developed for the sequential oxidation of benzyl alcohols and heteroaryl carbinols followed by the Pictet-Spengler cyclization and then aromatization to obtain the β-carbolines in high isolated yields. This methodology was found to be suitable for scale up and reusability. To the best of our knowledge, this is the first report on the oxidation of structurally diverse aryl carbinols and ODH of partially saturated N-heterocycles using a recyclable and heterogeneous photoredox catalyst under environmentally friendly conditions.

3-carbonyl-2H-benzopyran compounds or pharmaceutically acceptable salts thereof, preparation method and application of 3-carbonyl-2H-benzopyran compounds or pharmaceutically acceptable salts thereof

The invention discloses a 3-carbonyl-2H-benzopyran compound or a pharmaceutically acceptable salt thereof, a preparation method and application. The structural formula is shown in the specification. The compound plays a role of SERDs molecules, and is used for preparing medicines for treating or preventing various medical indications related to postmenopausal syndromes and treating ER (+) breast cancer.

Asymmetric Transfer Hydrogenation of Arylidene-Substituted Chromanones and Tetralones Catalyzed by Noyori-Ikariya Ru(II) Complexes: One-Pot Reduction of C═C and C═O bonds

3-Arylidenechroman-4-ones and 2-arylidene-1-tetralones are hydrogenated to cis-benzylic alcohols in dr's and er's up to 99:1 via a C═C and C═O one-pot reduction in the presence of 2-5 mol % Noyori-Ikariya-type RuII chiral complexes and HCO2Na as a hydroge