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776277-76-0

FMOC-HOMOARG-OH, also known as N-α-9-fluorenylmethyloxycarbonyl-N^ω-(2,2,5,7,8-pentamethylchromane-6-sulfonyl)-L-homoarginine, is a chemical compound widely utilized in peptide chemistry. It is a derivative of the amino acid homoarginine, characterized by the presence of an FMOC group that temporarily blocks reactive sites on the molecule, facilitating controlled and selective reactions during peptide synthesis. The chromane-6-sulfonyl group further protects the amino acid and can be easily removed under mild conditions, making FMOC-HOMOARG-OH an indispensable tool for constructing complex peptide structures in biological and pharmaceutical research.

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  • 776277-76-0 Structure

  • Basic information

    1. Product Name: FMOC-HOMOARG-OH
    2. Synonyms: FMOC-HOMOARG-OH;FMOC-HOMOARG-OH 98+%;Fmoc-HomoArginine;Fmoc-HoArg-OH;(S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-6-guanidinohexanoic acid;FMoc-Har-OH ] FMoc-L-HoMoarginine;N-FMoc-L-hoMoarginine, 96%;N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-homoarginine
    3. CAS NO:776277-76-0
    4. Molecular Formula: C22H26N4O4
    5. Molecular Weight: 410.47
    6. EINECS: N/A
    7. Product Categories: Unusual Amino Acids;Fmoc-Amino acid series
    8. Mol File: 776277-76-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: White/Powder
    5. Density: 1.35 g/cm3.
    6. Refractive Index: 1.649
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. PKA: 3.87±0.21(Predicted)
    10. CAS DataBase Reference: FMOC-HOMOARG-OH(CAS DataBase Reference)
    11. NIST Chemistry Reference: FMOC-HOMOARG-OH(776277-76-0)
    12. EPA Substance Registry System: FMOC-HOMOARG-OH(776277-76-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 776277-76-0(Hazardous Substances Data)

776277-76-0 Usage

Uses

Used in Peptide Synthesis:
FMOC-HOMOARG-OH is used as a protecting group in peptide synthesis for the controlled and selective reactions of homoarginine. The FMOC group shields the reactive sites, allowing for the stepwise assembly of peptide chains without unwanted side reactions.
Used in Pharmaceutical Research:
In the pharmaceutical industry, FMOC-HOMOARG-OH is used as a building block for the development of complex peptide-based drugs. Its ability to protect and later release the homoarginine residue under mild conditions enables the synthesis of peptides with specific therapeutic properties.
Used in Biological Research:
FMOC-HOMOARG-OH is employed as a component in the study of peptide interactions and functions in biological systems. Its controlled synthesis allows researchers to investigate the role of specific peptide sequences in various biological processes and diseases.
Overall, FMOC-HOMOARG-OH is a versatile compound in the fields of peptide chemistry, pharmaceutical research, and biological studies, playing a crucial role in the synthesis and investigation of complex peptide structures.

Check Digit Verification of cas no

The CAS Registry Mumber 776277-76-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,6,2,7 and 7 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 776277-76:
(8*7)+(7*7)+(6*6)+(5*2)+(4*7)+(3*7)+(2*7)+(1*6)=220
220 % 10 = 0
So 776277-76-0 is a valid CAS Registry Number.
InChI:InChI=1/C22H26N4O4/c23-21(24)25-12-6-5-11-19(20(27)28)26-22(29)30-13-18-16-9-3-1-7-14(16)15-8-2-4-10-17(15)18/h1-4,7-10,18-19H,5-6,11-13H2,(H,26,29)(H,27,28)(H4,23,24,25)/t19-/m0/s1

776277-76-0 Well-known Company Product Price

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  • TCI America

  • (F1014)  N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-homoarginine  >97.0%(HPLC)(T)

  • 776277-76-0

  • 1g

  • 590.00CNY

  • Detail

  • TCI America

  • (F1014)  N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-homoarginine  >97.0%(HPLC)(T)

  • 776277-76-0

  • 5g

  • 1,990.00CNY

  • Detail

  • Alfa Aesar

  • (H63228)  N-Fmoc-L-homoarginine, 96%   

  • 776277-76-0

  • 250mg

  • 704.0CNY

  • Detail

  • Alfa Aesar

  • (H63228)  N-Fmoc-L-homoarginine, 96%   

  • 776277-76-0

  • 1g

  • 2115.0CNY

  • Detail

  • Alfa Aesar

  • (H63228)  N-Fmoc-L-homoarginine, 96%   

  • 776277-76-0

  • 5g

  • 8443.0CNY

  • Detail

776277-76-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-6-(diaminomethylideneamino)-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid

1.2 Other means of identification

Product number -
Other names Fmoc-HomoArg

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:776277-76-0 SDS

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