7773-01-5 Usage
Physical Properties
The anhydrous chloride is a pink solid; cubic crystals; deliquescent; density 2.977 g/cm3 at 25°C; melts at 650°C; vaporizes at 1,190°C; very soluble in water (~72g/100 mL at 25°C); soluble in alcohol; insoluble in ether.
The tetrahydrate has a rose color; monoclinic crystal structure; deliquescent; density 2.01 g/cm3; melts at 58°C; loses one molecule of water at 106°C and all water at 198°C; highly soluble in water (151 g/100mL at 8°C) and extremely soluble in boiling water (656 g/100mL at 100°C); soluble in ethanol; insoluble in ether.
Uses
Different sources of media describe the Uses of 7773-01-5 differently. You can refer to the following data:
1. Manganese(II) chloride is used in dyeing and printing textiles and as a disinfectant. It also is used in dry cell batteries; for the preparation of drying agents for paints and varnishes; as a catalyst in chlorination reactions; in the production of several manganese salts, including methylcyclopentadienylmanganese tricarbonyl used as a colorant for brick. In metallurgy, the compound is used as an alloying agent and is added to molten magnesium to produce magnesium-manganese alloys.
2. A novel high-spin hexanuclear Mn(III) cluster, [NaMn6(OMe)12(dbm)6]+, was synthesized via MnCl2 oxidation with simultaneous NaOMe promoted aggregation. This cluster has an unprecedented cyclic structure and 24 unpaired electrons in its ground state.1 Also used in the formation of an active Mn(0) species useful for radical cyclization reactions.2
3. Used mainly in the production of dry cell batteries
4. Manganese chloride (MnCl2) is used in the pharmaceutical industry as a dietary supplement
and is added to fertilizers.
5. Manganese Chloride is a source of manganese that functions as a
nutrient and dietary supplement. it exists as crystals which are readily
soluble in room temperature (22°c) water and are very soluble in
hot water. see manganese.
Preparation
Manganese(II) chloride is prepared by heating manganese(II) oxide, manganese dioxide, manganese(II) carbonate or manganese(II) hydroxide with hydrochloric acid:
MnO2 + 4HCl → MnCl2 + 2H2O + Cl2
MnCO3 + HCl → MnCl2 + H2O + CO2
When the product mixture is evaporated below 58°C, the tetrahydrate salt, MnCl2?4H2O is obtained.
Manganese(II) chloride is a by-product in the manufacture of chlorine from manganese dioxide and hydrochloric acid (the Weldon process).
Anhydrous chloride can be prepared by heating manganese(II) oxide or manganese(II) carbonate with dry hydrogen chloride; or by burning the metal in chlorine at 700°C to 1,000°C.
The anhydrous salt can also be obtained by slowly heating the tetrahydrate, MnCl2?4H2O in a rotary drier above 200°C or by dehydration in a stream of hydrogen chloride gas.
Reactions
Manganese(II) chloride forms double salts with alkali metal chlorides when mixed in stoichiometric amounts. Such double salts, which can decompose in water, may have compositions like KMnCl3 or K2MnCl4.
Manganese(II) chloride forms adducts with ammonia, hydroxylamine and many other nitrogen compounds. Many adducts are stable at ordinary temperatures. Examples are MnCl2?6NH3 and MnCl2?2NH2OH.
An aqueous solution can readily undergo double decomposition reactions with soluble salts of other metals, producing precipitates of insoluble salts of Mn(II) or other metals.
Description
Manganese, an essential nutrient, occurs in many foods of plant
and animal origin. The naturally occurring manganese levels vary
from about 2 0 ppm in nuts, cereals, dried fruits and non-leafy
vegetables to less than 1 ppm in animal products.
Manganous chloride tetrahydrate is pink translucent crystals which
are very soluble in water.1
.
Chemical Properties
MnCl2 is rose-colored deliquescent crystals that are very soluble in water,and melts at 650°C and boils at 1190°C. The tetrahedral form, MnCI2.4H20 , melts at 58°C and loses its water at 198°C and is used as a catalyst in paints,dyes,pharmaceuticals, and fertilizers, and for various other purposes.
General Description
Manganese (II) chloride (MnCl2) might play a key role in integrin activation. Manganese is indispensable for brain function and is an essential cofactor for several key enzymes like superoxide dismutase and enzymes involved in neurotransmitter synthesis. Manganese can modulate iron and calcium homeostasis. Manganese is also used in the magnetic resonance imaging to increase contrast while examining neuronal connections and brain cytoarchitecture. High levels of manganese is toxic to central nervous system and causes Parkinson′s like symptoms called as manganism. MnCl2 has been used in reverse transcription reaction mix to enhance the template-switching efficiency.
Safety Profile
Poison by
intraperitoneal, subcutaneous, intramuscular,
intravenous, and parenteral routes.
Moderately toxic by ingestion. Experimental
teratogenic and reproductive effects.
Questionable carcinogen with experimental
carcinogenic data. Mutation data reported.
Explosive reaction when heated with zinc
foil. Reacts violently with potassium or
sodium. When heated to decomposition it
emits toxic fumes of Cl-. See also
MANGANESE COMPOUNDS and
CHLORIDES.
Check Digit Verification of cas no
The CAS Registry Mumber 7773-01-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,7 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7773-01:
(6*7)+(5*7)+(4*7)+(3*3)+(2*0)+(1*1)=115
115 % 10 = 5
So 7773-01-5 is a valid CAS Registry Number.
InChI:InChI=1/2ClH.Mn/h2*1H;/q;;+2/p-2
7773-01-5Relevant articles and documents
Chlorination of manganese oxides
Fouga, Gastón G.,De Micco, Georgina,Bohé, Ana E.
, p. 141 - 146 (2009)
In this work the reaction between several manganese oxides and chlorine is investigated. The reaction path for the chlorination of the oxides is established, which involves recrystallization of high valence manganese oxides: Mn3O4 an
MASS-SPECTROMETRIC MEASUREMENTS OF THERMODYNAMIC PROPERTIES OF THE MOLTEN KCl-MnCl2 SYSTEM.
Sasamoto,Itoh,Sata
, p. 2415 - 2419 (1983)
Activities and heats of mixing for the molten KCl-MnCl//2 system were determined mass-spectrometrically by the ion-current ratio method. Activities of components KCl and MnCl//2 show large negative deviations from Raoult's law, indicating a very strong interaction between KCl and MnCl//2. Entropies of mixing calculated from measured activities and heats of mixing have minimum values in the vicinity of 33% MnCl//2, and have been compared with those calculated on the basis of some molten structure models to infer possible chemical species in the molten salt.
Study on coordination behaviour of manganese chloride with L-α-histidine
Shengli,Sanping,Huanyong,Rongzu,Qizhen
, p. 795 - 805 (2004)
The reaction thermodynamic and kinetic equations for the non-reversible reactions are established. The enthalpy change of formation reaction of manganese(II) histidine (His) complex in water has been determined by microcalorimetry, using manganese chlorid
Pyridine-type complexes of transition-metal halides. Part XV. Mn(II) chloride complexes with 3,4- and 3,5-lutidine
Szecsenyi, K. Mészáros,Wadsten,Kovács,Liptay
, p. 965 - 974 (2004)
Manganese(II) chloride complexes with 3,4- and 3,5-lutidine have been prepared. The crystal symmetry and cell dimensions have been calculated on the basis of powder diffraction data. The compounds were characterised also by FT-IR spectrometry. The thermal
Evolution from discrete mononuclear complexes to trinuclear linear cluster and 2D coordination polymers of Mn(II) with dihydrazone Schiff bases: Preparation, structure and thermal behavior
Bourosh, Paulina N.,Bulhac, Ion,Ch. Kravtsov, Victor,Cocu, Maria,Croitor, Lilia,Danilescu, Olga,Petuhov, Oleg
, (2021)
Four Mn(II) coordination compounds based on the 2,6-diacetylpyridine bis(isonicotinoylhydrazone) (H2L1) and 2,6-diacetylpyridine bis(nicotinoylhydrazone) (H2L2), were prepared using different synthetic condition
Enhanced Stability of the FeII/MnII State in a Synthetic Model of Heterobimetallic Cofactor Assembly
Kerber, William D.,Goheen, Joshua T.,Perez, Kaitlyn A.,Siegler, Maxime A.
, p. 848 - 857 (2016)
Heterobimetallic Mn/Fe cofactors are found in the R2 subunit of class Ic ribonucleotide reductases (R2c) and R2-like ligand binding oxidases (R2lox). Selective cofactor assembly is due at least in part to the thermodynamics of MII binding to the apoprotein. We report here equilibrium studies of FeII/MnII discrimination in the biomimetic model system H5(F-HXTA) (5-fluoro-2-hydroxy-1,3-xylene-α,α′-diamine-N,N,N′,N′-tetraacetic acid). The homobimetallic F-HXTA complexes [Fe(H2O)6][1]2·14H2O and [Mn(H2O)6][2]2·14H2O (1 = [FeII2(F-HXTA)(H2O)4]-; 2 = [MnII2(F-HXTA)(H2O)4]-) were characterized by single crystal X-ray diffraction. NMR data show that 1 retains its structure in solution (2 is NMR silent). Metal exchange is facile, and the heterobimetallic complex [FeIIMnII(F-HXTA)(H2O)4]- (3) is formed from mixtures of 1 and 2. 19F NMR was used to quantify 1 and 3 in the presence of excess MII(aq) at various metal ratios, and equilibrium constants for FeII/MnII discrimination were calculated from these data. FeII is preferred over MnII with K1 = 182 ± 13 for complete replacement (2 21). This relatively modest preference is attributed to a hard-soft acid-base mismatch between the divalent cations and the polycarboxylate ligand. The stepwise constants for replacement are K2 = 20.1 ± 1.3 (2 23) and K3 = 9.1 ± 1.1 (3 21). K2 > K3 demonstrates enhanced stability of the heterobimetallic state beyond what is expected for simple MnII FeII replacement. The relevance to FeII/MnII discrimination in R2c and R2lox proteins is discussed.
Stevens, C. G.,Turkdogan, E. T.
, p. 370 - 373 (1954)
ALLan, J. R.,Brown, D. H.,Nuttall, R. H.,Sharp, D. W. A
, p. 1865 - 1867 (1965)
New complexes of 4-[(4-fluorophenyl)amino]-4-oxobut-2-enoic acid with selected transition metal ions: Synthesis, thermal, and magnetic properties
Ferenc,Sadowski,Tarasiuk,Cristóv?o,Osypiuk,Sarzyński
, p. 2719 - 2727 (2017/12/26)
Complexes of 4-[(4-fluorophenyl)amino]-4-oxobut-2-enoic acid, HL, with Mn(II), Co(II), Ni(II), Cu(II), Nd(III), Gd(III), and Er(III) were synthesized and characterized by various physico-chemical methods: elemental analysis, FT-IR, TG, DTG, DSC, TG/FT-IR, XRF, XRD, and magnetic measurements using the Gouy’s method and a SQUID-VSM magnetometer. The complexes were found to be hydrates (except Er(III) complex) containing 1 to 4 molecules of water. The carboxylate groups acted as bidentate ligands.
