78314-12-2

Basic information

• Product Name: 5-[[2-(Acetyloxy)acetyl]amino]-2,4,6-triiodo-1,3-benzenedicarbonyl Dichloride
• Synonyms: 5-[[(Acetyloxy)acetyl]aMino]-2,4,6-triiodo-1,3-benzenedicarbonyl Dichloride;5-[[2-(Acetyloxy)acetyl]amino]-2,4,6-triiodo-1,3-benzenedicarbonyl Dichloride
• CAS NO: 78314-12-2
• Molecular Formula: C₁₂H₆Cl₂I₃NO₅
• Molecular Weight: 695.79915
• Product Categories: Aromatics;Miscellaneous Reagents
• Mol File: 78314-12-2.mol

Chemical Properties

• Appearance: /
• Solubility: Chloroform
• CAS DataBase Reference: 5-[[2-(Acetyloxy)acetyl]amino]-2,4,6-triiodo-1,3-benzenedicarbonyl Dichloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[[2-(Acetyloxy)acetyl]amino]-2,4,6-triiodo-1,3-benzenedicarbonyl Dichloride(78314-12-2)
• EPA Substance Registry System: 5-[[2-(Acetyloxy)acetyl]amino]-2,4,6-triiodo-1,3-benzenedicarbonyl Dichloride(78314-12-2)

Safety Data

• Hazardous Substances Data: 78314-12-2(Hazardous Substances Data)

Usage

Uses

Intermediate in the production of contrast agents for X-ray imaging.

Upstream product

• 37441-29-5 5-amino-2,4,6-triiodoisophthalic acid dichloride 
• 13831-31-7 Acetoxyacetyl chloride 

Downstream Products

• 1143451-24-4 acetic acid 3-acetoxy-2-[3-(2-acetoxy-acetylamino)-5-chlorocarbonyl-2,4,6-triiodo-benzoylamino]-propyl ester 
• 1142238-60-5 acetic acid {3-chlorocarbonyl-5-[(2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-carbamoyl]-2,4,6-triiodo-phenylcarbamoyl}-methyl ester 
• 87771-40-2 ioversol 
• 78649-41-9 iomeprol 
• 77868-40-7 N₁,N₃-bis(2,3-dihydroxypropyl)-5-(2-hydroxyacetamido)-2,4,6-triiodobenzene-1,3-dicarboxamide 
• 1143451-60-8 acetic acid {3-chlorocarbonyl-5-[(5-hydroxymethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl)-carbamoyl]-2,4,6-triiodo-phenylcarbamoyl}-methyl ester 
• 1143451-59-5 acetic acid {3-chlorocarbonyl-5-[2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-2-hydroxy-ethylcarbamoyl]-2,4,6-triiodo-phenylcarbamoyl}-methyl ester 
• 1143451-52-8 acetic acid [3-chlorocarbonyl-5-(5-hydroxymethyl-2,2-dimethyl-[1,3]dioxan-5-ylcarbamoyl)-2,4,6-triiodo-phenylcarbamoyl]-methyl ester 
• 946506-16-7 acetic acid (3-chlorocarbonyl-5-diallylcarbamoyl-2,4,6-triiodo-phenylcarbamoyl)-methyl ester 
• 1142816-28-1 1,3-bis-[2-hydroxyacetylamino-5-[bis(2-hydroxyethyl)aminocarbonyl]-2,4,6-triiodo-benzoyl-amino]-2-hydroxypropane 
• 1097772-81-0 acetic acid {3-[bis-(2,3-dihydroxy-propyl)-carbamoyl]-5-chlorocarbonyl-2,4,6-triiodo-phenylcarbamoyl}-methyl ester 
• 946506-14-5 acetic acid [3-(allylcarbamoyl)-5-chlorocarbonyl-2,4,6-triiodo-phenylcarbamoyl]-methyl ester 
• 946506-30-5 acetic acid {3-chlorocarbonyl-5-[(2,3-dihydroxy-propyl)-methyl-carbamoyl]-2,4,6-triiodo-phenylcarbamoyl}-methyl ester 

Relevant articles and documents

New Methods for Preparing an Intermediate of Contrast Medium and Methods for Preparing Contrast Medium

A manufacturing method of the present invention reduces treatment processes when manufacturing a contrast medium or an intermediate thereof, and thus generates less waste solvent, thereby being eco-friendly and capable of significantly reducing a manufacturing cost. Therefore, the manufacturing method of the present invention is economical and suitable for mass production since the production cost of the contrast medium can be greatly reduced.

New Methods for Preparing an Intermediate of Contrast Medium and Methods for Preparing Contrast Medium

The present invention relates to a method for preparing an intermediate of contrast agent or contrast agent. Also, the manufacturing cost can be significantly reduced. , The manufacturing method of the present invention can greatly reduce the production cost of contrast agents and is suitable for mass production. (by machine translation)

preparation method of contrast agent

The present invention relates to a method for producing a contrast medium with high purity and high efficiency, and since no methyl iodide and the like are used in a production process, no salt is generated or only a very small amount thereof is generated, and a high purity and high efficiency contrast medium can be produced without complicated purification and washing steps. In addition, a small amount of salt can be easily removed by washing with water.COPYRIGHT KIPO 2018

CONTRAST AGENTS

Compounds of formula (I) RA—CO—N(R2)—(CR12)n—N(R5)—RB and salts or optical active isomers thereof, wherein each R1 independently are the same or different and denotes

CONTRAST AGENTS

The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing two lin

CONTRAST AGENTS

The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing a triamine alkyl central moiety allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging and to contrast media containing such compounds.

CONTRAST AGENTS

The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing a tris(aminoalkyl)amine group allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging and to contrast media containing such compounds.

CONTRAST AGENTS

The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing two lin

CONTRAST AGENTS

The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing two lin

CONTRAST AGENTS

The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing two lin