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78436-46-1

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78436-46-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 78436-46-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,8,4,3 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 78436-46:
(7*7)+(6*8)+(5*4)+(4*3)+(3*6)+(2*4)+(1*6)=161
161 % 10 = 1
So 78436-46-1 is a valid CAS Registry Number.

78436-46-1Downstream Products

78436-46-1Relevant articles and documents

Synthesis and stability of two indomethacin prodrugs

Chandrasekaran, Shyamala,Al-Ghananeem, Abeer M.,Riggs, Robert M.,Crooks, Peter A.

, p. 1874 - 1879 (2007/10/03)

The purpose of this study was to synthesize and study the in vitro enzymatic and non-enzymatic hydrolysis of indomethacin-TEG ester and amide prodrugs. It was found that the ester conjugate 10 was comparatively stable between pH 3 and 6 (half-life >90 h),

ESTERS OF 1-p-CHLOROBENZOYL-5-METHOXY-2-METHYL-3-INDOLYLACETIC ACID

Fisnerova, Ludmila,Rabek, Vlastimil,Nemecek, Oldrich

, p. 901 - 905 (2007/10/02)

Reactions of imidazolide of 1-p-chlorobenzoyl-5-methoxy-2-methyl-3-indolylacetic acid, prepared from the acid and N,N'-carbonyldiimidazole, with the optically active forms of 2-phenyl-3-hydroxypropane acid and with the inactive forms of p-chloro-, p-isopropyl- and p-isobutyl-2-phenyl-3-hydroxypropane acids gave the corresponding esters.The compounds were tested for antiinflammatory activity.

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