78823-41-3

Basic information

• Product Name: C₁₃H₁₆O₄
• Synonyms: C₁₃H₁₆O₄
• CAS NO: 78823-41-3
• Molecular Weight: 236.268
• Mol File: 78823-41-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₆O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₆O₄(78823-41-3)
• EPA Substance Registry System: C₁₃H₁₆O₄(78823-41-3)

Safety Data

• Hazardous Substances Data: 78823-41-3(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 100-09-4 4-methoxybenzoic acid 
• 201230-82-2 carbon monoxide 
• 459-64-3 4-methoxybenzenediazonium tetrafluoroborate 
• 1184-88-9 sodium pivalate 

Downstream Products

• 304668-44-8 (3,4-dihydroisoquinolin-2(1H)-yl)(4-methoxyphenyl)methanone 
• 72432-10-1 aniracetam 
• 7465-86-3 4-methoxy-N,N-diethylbenzamide 

Relevant articles and documents

Direct inter- and intramolecular addition of amides to arylalkenes promoted by KOt-Bu/DMF

Direct addition of tetrahydroisoquinoline derived amides to arylalkenes has been achieved in the presence of KOt-Bu/DMF. Both intermolecular and intramolecular reactions could occur in good yields. α-Amido alkyl radicals are proposed to be generated under the reaction conditions. The reaction is efficient for the synthesis of seven-membered nitrogen heterocycles. A homoprotoberberine was prepared conveniently via this method.

Reaction of Diazonium Salts with Transition Metals. 6. Preparation of Mixed Acid Anhydrides from Arenediazonium Salts and Sodium Carboxylates under Palladium(0) Catalysis

The palladium(0)-catalyzed reaction of arenediazonium tetrafluoroborates with carbon monoxide and sodium carboxylates in acetonitrile at 25 deg C gave mixed acid anhydrides, ArCOOCOR (Ar = 3-Me-Ph, 4-Me-Ph, 2-MeO-Ph, 4-Br-Ph, 4-I-Ph, 3-NO2-Ph, 4-NO2-Ph, and Ph; R = H, Me, Et, t-Bu, and Ph) in good yields.Homoaromatic acid anhydrides, (ArCO)2O, were obtained by heating of ArCOOCOMe at 100-120 deg C under vacuum.ArCOOCO-t-Bu can be utilized to obtain the corresponding arenecarboxamides by the reaction with some amines.