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Cas Database

79-37-8

79-37-8

Identification

  • Product Name:Oxalyl chloride

  • CAS Number: 79-37-8

  • EINECS:201-200-2

  • Molecular Weight:126.927

  • Molecular Formula: C2Cl2O2

  • HS Code:29171990

  • Mol File:79-37-8.mol

Synonyms:Oxalyl chloride (6CI,8CI);Ethanedioylchloride;Oxalic acid chloride;Oxalic acid dichloride;Oxalic dichloride;Oxaloyl chloride;Oxaloyldichloride;Oxalyl dichloride;Ethanedioyl dichloride;

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Safety information and MSDS view more

  • Pictogram(s):CorrosiveC, ToxicT

  • Hazard Codes:C,T

  • Signal Word:Danger

  • Hazard Statement:H260 In contact with water releases flammable gases which may ignite spontaneouslyH301+H331 Toxic if swallowed or if inhaled H314 Causes severe skin burns and eye damage

  • First-aid measures: General adviceConsult a physician. Show this safety data sheet to the doctor in attendance.If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

  • Fire-fighting measures: Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.

  • Accidental release measures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

  • Handling and storage: Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

  • Exposure controls/personal protection:Occupational Exposure limit valuesBiological limit values Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Respiratory protection Wear dust mask when handling large quantities. Thermal hazards

Supplier and reference price view more

  • Manufacture/Brand
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  • Manufacture/Brand:TRC
  • Product Description:Oxalyl chloride
  • Packaging:500g
  • Price:$ 185
  • Delivery:In stock
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  • Manufacture/Brand:TRC
  • Product Description:Oxalyl chloride
  • Packaging:50g
  • Price:$ 45
  • Delivery:In stock
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  • Manufacture/Brand:TCI Chemical
  • Product Description:Oxalyl Chloride >98.0%(GC)(T)
  • Packaging:500g
  • Price:$ 224
  • Delivery:In stock
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  • Manufacture/Brand:TCI Chemical
  • Product Description:Oxalyl Chloride >98.0%(GC)(T)
  • Packaging:100g
  • Price:$ 61
  • Delivery:In stock
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  • Manufacture/Brand:TCI Chemical
  • Product Description:Oxalyl Chloride >98.0%(GC)(T)
  • Packaging:25g
  • Price:$ 27
  • Delivery:In stock
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  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:Oxalyl chloride
  • Packaging:1 kg
  • Price:$ 512
  • Delivery:In stock
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  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:Oxalyl chloride
  • Packaging:250 g
  • Price:$ 159
  • Delivery:In stock
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  • Manufacture/Brand:SynQuest Laboratories
  • Product Description:Oxalyl chloride
  • Packaging:100 g
  • Price:$ 112
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Oxalyl chloride ReagentPlus , ≥99%
  • Packaging:100g
  • Price:$ 112
  • Delivery:In stock
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  • Manufacture/Brand:Sigma-Aldrich
  • Product Description:Oxalyl chloride solution 2.0 M in methylene chloride
  • Packaging:800ml
  • Price:$ 174
  • Delivery:In stock
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Relevant articles and documentsAll total 22 Articles be found

In silico design and pharmacological evaluation of conjugates of atenolol with modified saccharide for cardiovascular targeting

Kumbhar, Smita Tukaram,Patil, Shitalkumar Shivgonda,Bhatia, Manish Sudesh

, p. 261 - 271 (2021)

Amongst a wide range of biological macromolecules, saccharides exhibit the potential to be specifically recognized by cell-surface receptors and hence can be utilized as ligands in targeted drug delivery. The current study aims to use saccharides viz. Galactose, Pectin and Chitosan to improve targeting of Atenolol by oxalyl chloride mediated grafting. Conjugates were engineered by grafting Atenolol, a cardiovascular agent with the modified saccharide units. The conjugates were characterized by FTIR, DSC and 1H NMR study. Drug release analysis and cellular uptake study was carried out using H9c2 cell lines which represent that concentration of drug in cells treated with all atenolol-saccharide conjugates is enhanced by almost two-folds in comparison with cells treated with atenolol solution. Thus cell line study confers the evidence of selective cardiac delivery. No significant cytotoxicity was observed in case of all synthesized conjugates in the Brine shrimp lethality bioassay. Possible binding of the developed conjugates with the GLUT-4 receptors was assessed by in silico analysis using homology model developed by Swiss Model server. Hence it was concluded that the application of these conjugates with saccharides in selective cardiovascular drug delivery can be a promising approach to increase bioavailability, minimize drug loss by degradation and prevent harmful side effects by increasing specific cell targeting. Graphical abstract: [Figure not available: see fulltext.]

Citrate plasticizer and preparation method thereof

-

Paragraph 0054; 0057, (2021/05/29)

The invention discloses a citrate plasticizer and a preparation method thereof. The preparation method comprises the following steps: firstly, carrying out reaction on citric acid and alcohol to prepare citric acid triester; acylating dianhydride to prepare carboxyl-containing triester citrate; carrying out acylating chlorination on the carboxyl-containing triester citrate, and then carrying out esterification reaction on the carboxyl-containing triester citrate and tri(2-hydroxyethyl) isocyanurate to prepare triester citrate containing isocyanurate; and finally, esterifying with fatty acyl chloride to obtain the modified citrate plasticizer. The preparation method is simple to operate, wide in raw material source and mild in reaction condition, and meets industrial production. The prepared triester citrate containing isocyanurate has a good plasticizing effect and excellent thermal stability, low-temperature flexibility, solvent extraction resistance, migration resistance and flame retardance, and can be widely applied to plastic rubber plasticizers.

Sensor Comprising Resrufin Levulinate Having Sulfite Ion Selectivity and Method for Monitoring Sulfite Ion Using the Same

-

, (2012/06/16)

The present invention relates to a sensor comprising a resorufin compound having sulfite ion selectivity and a method for detecting sulfite ions using the same. More specifically, the resorufin compound may have outstandingly increased fluorescence intensity by a deprotection reaction that a levulinyl group is cleaved with a sulfite ion to be used as a selective fluorescence sensor of turn-on type, and also represent a chromogenic change to detect sulfite ions by naked eye.

Process route upstream and downstream products

Process route

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

oxalyl dichloride
79-37-8

oxalyl dichloride

chloroethane
75-00-3

chloroethane

1,2-diethoxy-tetrachloro-ethane
63938-37-4

1,2-diethoxy-tetrachloro-ethane

ethoxy-dichloro-acetyl chloride
98019-44-4

ethoxy-dichloro-acetyl chloride

Ethyl oxalyl chloride
4755-77-5

Ethyl oxalyl chloride

Conditions
Conditions Yield
With phosphorus pentachloride; manganese(ll) chloride; at 90 ℃; for 5h; Product distribution; other catalysts (CuCl2, ZnCl2, CdCl2, CrCl3, FeCl3, CoCl2, PdCl2) and temperatures (from 70 to 130 deg C);
83.7%
1,2-diethoxy-tetrachloro-ethane
63938-37-4

1,2-diethoxy-tetrachloro-ethane

oxalyl dichloride
79-37-8

oxalyl dichloride

chloroethane
75-00-3

chloroethane

ethoxy-dichloro-acetyl chloride
98019-44-4

ethoxy-dichloro-acetyl chloride

Conditions
Conditions Yield
at 165 ℃;
oxalyl dichloride
79-37-8

oxalyl dichloride

dichloromethane
75-09-2

dichloromethane

Conditions
Conditions Yield
Trichloroethylene
79-01-6

Trichloroethylene

dichloroacethyl chloride
79-36-7

dichloroacethyl chloride

oxalyl dichloride
79-37-8

oxalyl dichloride

chloral
75-87-6

chloral

1,1,2-trichloroethan-2-ol
13287-89-3

1,1,2-trichloroethan-2-ol

Conditions
Conditions Yield
With BaY-coated optical fibers; oxygen; Product distribution; Irradiation;
pyridine
110-86-1

pyridine

bis(trichloromethyl) oxalate
98020-90-7

bis(trichloromethyl) oxalate

chlorobenzene
108-90-7

chlorobenzene

phosgene
75-44-5

phosgene

oxalyl dichloride
79-37-8

oxalyl dichloride

Conditions
Conditions Yield
2,3-dichloro-5,6-difluoro-1,4-dioxin
133349-04-9

2,3-dichloro-5,6-difluoro-1,4-dioxin

oxalyl dichloride
79-37-8

oxalyl dichloride

Carbonyl fluoride
353-50-4

Carbonyl fluoride

oxalyl difluoride
359-40-0

oxalyl difluoride

C<sub>3</sub>Cl<sub>2</sub>F<sub>2</sub>O<sub>3</sub>

C3Cl2F2O3

C<sub>3</sub>Cl<sub>2</sub>F<sub>2</sub>O<sub>3</sub>

C3Cl2F2O3

C<sub>4</sub>Cl<sub>2</sub>F<sub>2</sub>O<sub>3</sub>

C4Cl2F2O3

Conditions
Conditions Yield
With oxygen;
oxalyl dichloride
79-37-8

oxalyl dichloride

Conditions
Conditions Yield
With phosphorus pentachloride; trichlorophosphate;
With phosphorus pentachloride;
With phosphorus pentachloride;
With phosphorus pentachloride; Heating;
With pyridine; bis(trichloromethyl) carbonate; In dichloromethane; at 5 - 10 ℃; for 3.5h; Reagent/catalyst; Solvent;
With thionyl chloride; In dichloromethane; at 40 - 45 ℃; for 3.5h;
With phosphorus trichloride; at 60 ℃;
3-(tert-butyloxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid

3-(tert-butyloxycarbonyl)bicyclo[1.1.1]pentane-1-carboxylic acid

oxalyl dichloride
79-37-8

oxalyl dichloride

Conditions
Conditions Yield
With triethylamine; trifluoroacetic acid; In tetrahydrofuran; [(2)H6]acetone; n-heptane; dichloromethane;
7-hydroxy-3H-phenoxazin-3-one sodium salt
34994-50-8

7-hydroxy-3H-phenoxazin-3-one sodium salt

levulinic acid
123-76-2

levulinic acid

oxalyl dichloride
79-37-8

oxalyl dichloride

Conditions
Conditions Yield
With triethylamine; In dichloromethane; water;
4-fluoroanthranilic acid
446-32-2

4-fluoroanthranilic acid

oxalyl dichloride
79-37-8

oxalyl dichloride

Conditions
Conditions Yield
In formamide; at 150 ℃; for 6h;
82%

Global suppliers and manufacturers

Global( 139) Suppliers
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  • Hangzhou Dingyan Chem Co., Ltd
  • Business Type:Trading Company
  • Contact Tel:86-571-86465881,86-571-87157530,86-571-88025800
  • Emails:sales@dingyanchem.com
  • Main Products:95
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  • Simagchem Corporation
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  • Contact Tel:+86-592-2680277
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  • Main Products:110
  • Country:China (Mainland)
  • EAST CHEMSOURCES LIMITED
  • Business Type:Manufacturers
  • Contact Tel:86-532-81906761
  • Emails:josen@eastchem-cn.com
  • Main Products:97
  • Country:China (Mainland)
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