79127-80-3 Usage
Description
Fenoxycarb is a carbamate insect growth regulator. Fenoxycarb is a yellow granular solid,
broad-spectrum insect growth regulator, and non-neurotoxic carbamate. Fenoxycarb is
almost insoluble in water but soluble and very soluble in hexane, acetone, chloroform,
diethyl ether, and methanol. Fenoxycarb is a general use pesticide (GUP), meaning the
user or the pesticide applicator does not need a licence. It is used to control a wide variety
of insect pests, such as fire ant bait and for flea and mosquito. It is also used for the control
of cockroaches, butterflies, moths, beetles, scale, and sucking insects on olives, vines,
cottons, and fruits. It is also used to control these pests on stored products. As a growth
regulator, fenoxycarb blocks the ability of an insect to change into the adult stage from
the juvenile stage (metamorphosis). Fenoxycarb interferes with larval moulting, the periodic
shedding or moulting of the old exoskeleton, and production of a new exoskeleton.
Although fenoxycarb is a carbamate insecticide, it exhibits no anti-cholinesterase activity
and is thus considered non-neurotoxic. It mimics the action of the juvenile hormones (JHs)
on a number of physiological processes, such as moulting and reproduction in insects.
Chemical Properties
Fenoxycarb is a yellow granular solid, broad-spectrum insect growth regulator and nonneurotoxic carbamate. Fenoxycarb is almost insoluble in water, but soluble and very soluble in hexane, acetone, chloroform, diethyl ether, and methanol. Fenoxycarb is a GUP, meaning the user or the pesticide applicator does not need a license. It is used to control a wide variety of insect pests, as a fi re ant bait and for fl ea and mosquito control. It is also used for the control of cockroaches, butterfl ies, moths, beetles, scale, and sucking insects, pests of stored products. As a growth regulator, fenoxycarb blocks the ability of an insect to change into the adult stage from the juvenile stage (metamorphosis). Fenoxycarb interferes with larval molting, the periodic shedding or molting of the old exoskeleton and production of a new exoskeleton. Although fenoxycarb is a carbamate insecticide, it exhibits no anticholinesterase activity and is thus considered non-neurotoxic. It is useful for the control of fi re ants, fl eas, mosquitoes, cockroaches, moths, scale insects, and insects attacking vines, olives, cotton, and fruit. It is also used to control these pests on stored products, and is often formulated as a grit or corncob bait. It mimics the action of the juvenile hormones (JH) on a number of physiological processes, such as molting and reproduction in insects.
Uses
Fenoxycarb is mainly used to control Lepidoptera, scale insects
and suckers on fruit, cotton, olives, vines and ornamentals. It is used to
control Coleoptera and Lepidoptera in stored products, and cockroaches,
fleas, mosquito larvae and fire ants in public health situations.
Health Hazard
Fenoxycarb is practically non-toxic to mammals after oral ingestion. The oral LD50 for rats is greater than 10,000 mg/kg and the dermal LD50 for rats is greater than 2,000 mg/ kg. Direct application of fenoxycarb on the skin of laboratory rats caused labored breathing and diarrhea in animals. Although fenoxycarb does not irritate the skin, it is an eye irritant. The liver is the primary organ affected by fenoxycarb in long-term animal studies. Prolonged period of oral exposures to rats and dogs with very low doses of fenoxycarb caused no health effects in the animals, while high concentrations caused adverse effects to the liver of rats, mice, and dogs. Reports on the teratogenicity and mutagenicity of fenoxycarb are not available in the literature.
Metabolic pathway
When the insect larvae of tobacco budworm are fed
with 14C-fenoxycarb, at the time of gut purge, the
whole of the radio-labeled material is excreted. The
main metabolites of fenoxycarb are identified and
show hydroxylation of the aromatic rings which makes
the excretion easier. Cleavage of the molecule to give
carboxylic acid metabolites confirms the hypothesis
that the fenoxycarb is not cleaved by esterase.
Degradation
Solutions of [14C-1,4-phenoxy]fenoxycarb in aqueous buffers (pH 3, 7, 9)
were maintained at 35 °C for 70 days. The compound was stable over
this period (PSD, 1997). In a study to US EPA guidelines, a solution of
[14C-1,4-phenoxy]fenoxycarb in sterile buffer at pH 7 and at 25 °C was
irradiated with a xenon arc lamp. Light of wavelength less than 290 nm
was filtered out. Irradiation was equivalent to one year of average midday
sunlight at 40-50°N. Additional tests were done using acetone as a
photosensitiser. Samples were analysed using LSC and HPLC methods.
Little 14CO2 was evolved and 80 and 40% of the parent fenoxycarb
degraded within 210 minutes in the sensitised and unsensitised samples,
respectively. Seven photoproducts were identified from the unsensitised
samples but only the phenol (2) was formed (see Scheme 1) in appreciable
amount (12.3% of applied radioactivity after 6 hours) (PSD, 1997).
Check Digit Verification of cas no
The CAS Registry Mumber 79127-80-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,9,1,2 and 7 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 79127-80:
(7*7)+(6*9)+(5*1)+(4*2)+(3*7)+(2*8)+(1*0)=153
153 % 10 = 3
So 79127-80-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H19NO4/c1-2-20-17(19)18-12-13-21-14-8-10-16(11-9-14)22-15-6-4-3-5-7-15/h3-11H,2,12-13H2,1H3,(H,18,19)
79127-80-3Relevant articles and documents
SYSTEM FOR PROTECTING GOODS DURING TRANSPORT
-
, (2013/02/28)
A system for protecting stored goods in a container (10), comprises a cage-like structure (20) formed by at least one pesticide treated net (22), capable of enclosing the stored goods, wherein the cage like structure (20), further comprises means for suspending the pesticide treated nets (14, 28, 30, 32, 34), and means for opening and closing the cage-like structure (26) on at least one section (24) of the at least one net (22). The system is particularly useful for the transport of tobacco, coffee, dried fruits, cocoa, nuts, tea, cereals, vegetables, spices and animals.
PROCESS AND MEANS FOR THE ERADICATION OF TICKS IN THE HABITATS OF SMALL MAMMALS
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, (2008/06/13)
Disclosed is a process for using a compound according to formula (I) or formula (II) to prepare a mixture for the eradication of ticks in the living quarters of small mammals, especially cats and dogs. Said process consists in applying as needed to the animal or animals of the habitat concerned a topical formulation in sufficiently pesticidal quantities of a compound according to formula (I), or possibly formula (II), at monthly intervals.
Insecticidal compositions and methods of use employing imidacloprid and another insecticide
-
, (2008/06/13)
The present invention relates to insecticidal mixtures of chloronicotinyl insecticides of the formula (I) STR1 in which R1 represents C1 -C5 -alkyl, R2 represents hydrogen or C1 -C5 -alkyl, or R1 and R2 together represent --CH2 --CH2 --; --CH2 --CH2 --CH2 -- or STR2 X represents an NH group, NCH3 group or represents sulphur, Y represents nitrogen or a CH group and Z represents cyano or nitro, with one or more of the synergists mentioned in the description.
