79960-76-2

Basic information

• Product Name: (2-ethoxycarbonyloxy-benzoyl)-carbonic acid ethyl ester
• Synonyms: (2-ethoxycarbonyloxy-benzoyl)-carbonic acid ethyl ester
• CAS NO: 79960-76-2
• Molecular Weight: 282.25
• Mol File: 79960-76-2.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (2-ethoxycarbonyloxy-benzoyl)-carbonic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2-ethoxycarbonyloxy-benzoyl)-carbonic acid ethyl ester(79960-76-2)
• EPA Substance Registry System: (2-ethoxycarbonyloxy-benzoyl)-carbonic acid ethyl ester(79960-76-2)

Safety Data

• Hazardous Substances Data: 79960-76-2(Hazardous Substances Data)

Upstream product

• 541-41-3 chloroformic acid ethyl ester 
• 69-72-7 salicylic acid 
• 14216-33-2 2-ethoxycarbonyloxy-benzoic acid 
• 110-86-1 pyridine 

Downstream Products

• 2037-99-2 3-benzyl-2H-benzo[e][1,3]oxazine-2,4(3H)-dione 

Relevant articles and documents

Convenient preparation of primary amides via activation of carboxylic acids with ethyl chloroformate and triethylamine under mild conditions

Primary amides were easily prepared in 22-99% yields from the corresponding carboxylic acids 1 or 5 with NH4Cl via activation with ClCO 2Et and Et3N. The enantiomers of the corresponding primary amides of Cbz-, Boc-, or Fmoc-α-amino acids can be separated by using a chiral column.

THALIDOMIDE ANALOGS

Thalidomide analogs that modulate tumor necrosis factor alpha (TNF-α) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs.