80213-12-3

Basic information

• Product Name: 4-Piperidinol, 1-[(4-methylphenyl)sulfonyl]-
• CAS NO: 80213-12-3
• Molecular Formula: C12H17NO3S
• Molecular Weight: 255.338
• Mol File: 80213-12-3.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 4-Piperidinol, 1-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinol, 1-[(4-methylphenyl)sulfonyl]-(80213-12-3)
• EPA Substance Registry System: 4-Piperidinol, 1-[(4-methylphenyl)sulfonyl]-(80213-12-3)

Safety Data

• Hazardous Substances Data: 80213-12-3(Hazardous Substances Data)

Upstream product

• 5382-16-1 4-HYDROXYPIPERIDINE 
• 98-59-9 p-toluenesulfonyl chloride 
• 41979-39-9 4-piperidone hydrochloride 
• 4727-72-4 1-benzyl-4-hydroxypiperidine 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 289890-80-8 4-iodo-1-[(4-methylphenyl)sulfonyl]piperidine 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 40064-34-4 piperidine-4,4-diol hydrochloride 

Downstream Products

• 93148-69-7 4-(2-methylprop-1-en-1-yl)-1-tosylpiperidine 
• 1373334-63-4 4-allyl-1-tosylpiperidine 
• 922504-26-5 phenyl(1-tosylpiperidin-4-yl)methanone 
• 57186-75-1 1-tosyl-1,2,5,6-tetrahydropyridine 
• 4703-22-4 N-tosylpiperidine 
• 101767-94-6 1-<(4-methylphenyl)sulfonyl>-4-piperidinol 4-methylbenzenesulfonate ester 
• 928256-40-0 4-(4-methoxyphenyl)-1-tosylpiperidine 
• 347885-68-1 4-bromo-1-tosylpiperidine 

Relevant articles and documents

Nickel-Catalyzed Cyanation of Unactivated Alkyl Sulfonates with Zn(CN)2

Cyanation of unactivated primary and secondary alkyl mesylates with Zn(CN)2 catalyzed by nickel has been developed. The reaction provides an efficient route for the synthesis of alkyl nitriles with wide substrate scope, good functional group tolerance, and compatibility with heterocyclic compounds. Mechanistic studies indicate that alkyl iodide generated in situ serves as the reactive intermediate and the gradual release of alkyl iodide is crucial for the success of the reaction.

Copper-Catalyzed and Indium-Mediated Methoxycarbonylation of Unactivated Alkyl Iodides with Balloon CO

This work emphasizes the synthesis of alkyl esters via Cu-catalyzed and In-mediated alkoxycarbonylation of unactivated alkyl iodides in the presence of In or InI. The reactions were suitable for the preparation of primary, secondary, and even tertiary alkyl esters, representing an exceptionally rare example for the creation of quaternary carbon centers upon formation of esters. The preliminary mechanistic studies indicated that alkyl radicals were involved, and Cu/In/CO played a cooperative role in the carbonylation event.

Visible-Light-Mediated Aerobic Oxidation of Organoboron Compounds Using in Situ Generated Hydrogen Peroxide

A simple and general visible-light-mediated oxidation of organoboron compounds has been developed with rose bengal as the photocatalyst, substoichiometric Et3N as the electron donor, as well as air as the oxidant. This mild and metal-free protocol shows a broad substrate scope and provides a wide range of aliphatic alcohols and phenols in moderate to excellent yields. Notably, the robustness of this method is demonstrated on the stereospecific aerobic oxidation of organoboron compounds.