80790-68-7 Usage
General Description
The chemical compound "(1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-morpholin-4-yl-alpha-L-lyxo-hexopyranoside" is a complex molecule with a tetracycline structure. It contains a tetracycline core with several hydroxy and methoxy functional groups, as well as a hydroxyacetyl and a morpholin-4-yl-alpha-L-lyxo-hexopyranoside side chain. (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 2,3,6-trideoxy-3-morpholin-4-yl-alpha-L-lyxo-hexopyranoside is commonly used as an antibiotic, specifically as a broad-spectrum bacteriostatic agent. It works by inhibiting the protein synthesis in bacteria, thereby preventing their growth and multiplication. Due to its antibiotic properties, it is widely used in the treatment of various bacterial infections.
Check Digit Verification of cas no
The CAS Registry Mumber 80790-68-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,0,7,9 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 80790-68:
(7*8)+(6*0)+(5*7)+(4*9)+(3*0)+(2*6)+(1*8)=147
147 % 10 = 7
So 80790-68-7 is a valid CAS Registry Number.
80790-68-7Relevant articles and documents
Intensely potent morpholinyl anthracyclines
Acton,Tong,Mosher,Wolgemuth
, p. 638 - 645 (2007/10/02)
3'-Deamino-3'-(3-cyano-4-morpholinyl)doxorubicin is a new analogue that is 100 to 1000 times more potent than doxorubicin against tumors in cell culture or in mice, that is active by intraperitoneal, intravenous, or oral dosing, and that does not produce chronic myocardial lesions in mice. This analogue was encountered in studies on the reductive alkylation of doxorubicin and daunorubicin with 2,2'-oxybis[acetaldehyde], which constructs a morpholino ring incorporating the amino N. The morpholinyl nitrile byproducts are separated by virtue of their nonbasicity from the expected morpholino derivatives. The 13-dihydro and 5-imino derivatives are also described in this important new class of anthracyclines.
