80868-49-1

Basic information

• Product Name: (1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester
• CAS NO: 80868-49-1
• Molecular Weight: 352.517
• Mol File: 80868-49-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester(80868-49-1)
• EPA Substance Registry System: (1R,2R,4R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (1S,2R,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester(80868-49-1)

Safety Data

• Hazardous Substances Data: 80868-49-1(Hazardous Substances Data)

Upstream product

• 72526-00-2 (-)-8-phenylmenthyl acrylate 
• 542-92-7 cyclopenta-1,3-diene 
• 100101-42-6 (1S,2R,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexanol 
• 100020-75-5 (1S,2R,5R)-5-methyl-2-(1-methyl-1-phenylethyl)cyclohexyl acrylate 
• 65253-04-5 (-)-8-phenylmenthol 

Relevant articles and documents

Mixed-Ligand Arenechromium Carbonyl Complexes as Electronic Modulators

A number of mixed ligand η6 arenechromium carbonyl complexes have been prepared and investigated for their ability to effect electronic modulation of arene chemistry. In the case of an aniline-derived system, the arenechromium carbonyl complex is able to modulate the inductive capacity of the aniline nitrogen atom and thus, regulate its anchimeric ability. In the case of 8-phenylmenthol and benzyloxazolidinone derivatives, modulation of arene π basicity is achieved, and results suggest that important vinylarene π-π interactions exist in acrylate derivatives of these chiral auxiliary systems.

Fluorinated alcohols as solvents for Diels-Alder reactions of chiral acrylates

Fluorinated alcohols increase the rates of endo/exo selectivities of the Diels-Alder reactions of cyclopentadiene with (-)-menthyl and (-)-8-phenylmenthyl acrylates. The use of fluorinated alcohols also increases the diastereofacial selectivity in the reactions of (-)-menthyl acrylate, but decreases it when the dienophile is (-)-8-phenylmenthyl acrylate. These facts are accounted for by the conformational preferences of the dienophile in non-HBD solvents and by the tendency of fluorinated alcohols to shift the conformational equilibrium towards the s-trans conformation.

Preparation of 8-Phenylmenthol and Its Diastereomer, 2-epi,ent-8-Phenylmenthol. A Caveat

-