811-68-7

Basic information

• Product Name: (Trifluoromethylthio) silver(I)
• Synonyms: (Trifluoromethylthio) silver(I);[(Trifluoromethyl)thio] silver(I);Silver(I)trifluoromethanethiolate
• CAS NO: 811-68-7
• Molecular Formula: CAgF₃S
• Molecular Weight: 209.94
• Mol File: 811-68-7.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Water Solubility: Insoluble in water
• CAS DataBase Reference: (Trifluoromethylthio) silver(I)(CAS DataBase Reference)
• NIST Chemistry Reference: (Trifluoromethylthio) silver(I)(811-68-7)
• EPA Substance Registry System: (Trifluoromethylthio) silver(I)(811-68-7)

Safety Data

• Hazardous Substances Data: 811-68-7(Hazardous Substances Data)

Usage

General Description

(Trifluoromethylthio) silver(I) is a type of organosilver compound known for its roles in synthetic organic chemistry. The chemical formula for this compound is AgSCF3. It is often used as a reagent in the application of trifluoromethylthiolation, where it functions as a source of the trifluoromethylthio group. (Trifluoromethylthio) silver(I) is typically prepared via the reaction of silver(I) oxide and trifluoromethanethiol. Despite its usefulness, it is extremely sensitive to moisture and must be handled with care.

Upstream product

• 753-94-6 trifluoro methyl silyl sulfide 
• 506-64-9 silver(I) cyanide 
• 420-32-6 thiocarbonyl fluoride 
• 11113-87-4 silver fluoride 
• 330660-35-0 silver cyanide 
• 563-63-3 silver(I) acetate 
• 21259-75-6 mercury bis(trifluoromethanethiolate) 
• 75-15-0 carbon disulfide 
• 1493-15-8 trifluoromethylsulfide 
• 78910-20-0 F₃CSe(O)OAg 
• 15223-20-8 1-methyl-4-{[(trifluoromethyl)sulfanyl]sulfonyl}benzene 
• 14104-20-2 silver tetrafluoroborate 
• 2926-29-6 Langlois reagent 
• 26042-63-7 silver(I) hexafluorophosphate 

Downstream Products

• 2408-13-1 <4-Carboxy-benzyl>-trifluormethyl-sulfid 
• 78134-79-9 {3-[(trifluoromethyl)sulfanyl]prop-1-yn-1-yl}benzene 
• 29848-64-4 Benzaldehyd-bistrifluormethylmercaptal 
• 372-64-5 Bis(trifluoromethyl)disulfid 
• 39566-17-1 1-(4-nitrophenyl)-2-((trifluoromethyl)thio)ethanone 
• 420-32-6 thiocarbonyl fluoride 
• 37771-97-4 N-phenylbenzenecarboximidoyl fluoride 
• 456-56-4 phenyl trifluoromethylsulfide 
• 420-56-4 trimethylsilyl fluoride 
• 352-68-1 4-trifluoromethylthiotoluene 
• 403-66-7 p-nitrophenyl trifluoromethyl sulfide 
• 50404-64-3 trans-{Ir(SCF₃)(CO)(P(C₆H₅)3)2} 
• 24628-90-8 tris(trifluoromethyl) benzeneorthotrithiobenzoate 
• 3872-23-9 Copper(I) trifluoromethanethiolate 

Relevant articles and documents

Ammonium Chloride-Mediated Trifluoromethylthiolation of p-Quinone Methides

Ammonium chloride-mediated trifluoromethylthiolation of p-quinone methides is reported using inexpensive and bench stable AgSCF3 as a nucleophilic trifluoromethylthiolating (-SCF3) reagent. This method is an efficient strategy for the construction of the benzylic C(sp3)-SCF3 bond to synthesize trifluoromethylthio-diarylmethane derivatives by 1,6-conjugate addition/aromatization under mild reaction conditions without any metal catalyst, oxidants, or additives. This is the first report of trifluoromethylthiolation of p-quinone methides. In addition, di-trifluoromethylthiolation of δ-chloro-p-quinone methide and scalability are demonstrated.

Silver-mediated radical aryltrifluoromethylthiolation of activated alkenes by S-trifluoromethyl 4-methylbenzenesulfonothioate

Herein, we describe the preparation of trifluoromethylthiol-substituted oxindoles by silver-mediated aryltrifluoromethylthiolation of activated alkenes, using S-trifluoromethyl 4-methylbenzenesulfonothioate as a F3CS radical source and showing that the reagent availability, mild conditions, and broad functional group compatibility of this transformation make it a viable alternative strategy of constructing Csp3–SCF3 bonds.