81477-68-1

Basic information

• Product Name: 2-iodo-3,6-bis<(tert-butyldimethylsilyl)oxy>cinnamaldehyde
• CAS NO: 81477-68-1
• Molecular Weight: 518.583
• Mol File: 81477-68-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-iodo-3,6-bis<(tert-butyldimethylsilyl)oxy>cinnamaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-iodo-3,6-bis<(tert-butyldimethylsilyl)oxy>cinnamaldehyde(81477-68-1)
• EPA Substance Registry System: 2-iodo-3,6-bis<(tert-butyldimethylsilyl)oxy>cinnamaldehyde(81477-68-1)

Safety Data

• Hazardous Substances Data: 81477-68-1(Hazardous Substances Data)

Upstream product

• 71255-05-5 2-iodo-3,6-dimethoxybenzyl vinyl ether 
• 71255-03-3 2,5-dimethoxybenzyl vinyl ether 
• 71255-06-6 2-iodo-3,6-dimethoxybenzyl alcohol 
• 70738-04-4 2-iodo-3,6-dimethoxybenzaldehyde 
• 70738-05-5 2-iodo-3,6-dihydrobenzaldehyde 
• 33524-31-1 2,5-dimethoxybenzyl alcohol 
• 81477-61-4 2-iodo-3,6-bis<(tert-butyldimethylsilyl)oxy>benzaldehyde 

Downstream Products

• 81477-70-5 5-<2-iodo-3,6-bis(tert-butyldimethylsiloxy)phenyl>-2,4-pentadienal 
• 81477-71-6 1-<2-iodo-3,6-bis(tert-butyldimethylsiloxy)phenyl>-1,3-undecadien-5-ol 
• 81477-65-8 1-<2-iodo-3,6-bis(tert-butyldimethylsiloxy)phenyl>-1,3,5-undecatriene 
• 73151-59-4 (7E,9E,11E)-aurocitrin 

Relevant articles and documents

Total Synthesis of Frustulosin and Aurocitrin

The regioselective total syntheses of the novel fungal antibiotics frustulosin (1) and aurocitrin (2) were accomplished from 3,6-dihydroxy-2-iodobenzaldehyde (10) which was prepared by a regiodirected metalation of 2,5-dimethylbenzyl vinyl ether to establish the 1,2,3,4-tetrasubstitution pattern of these compounds.The unsaturated side chains of these hydroquinone antibiotics were attached by using the iodo aldehyde functionalities.The structures of these antibiotics are confirmed by synthesis.