825-25-2

Basic information

• Product Name: 2-CYCLOPENTYLIDENECYCLOPENTANONE
• Synonyms: 2-CYCLOPENTYLIDENE-1-CYCLOPENTANONE;2-CYCLOPENTYLIDENECYCLOPENTANONE;cyclopentylidenecyclopentan-2-one;2-Cyclopentylidenecyclopentane-1-one;Δ1,1'-Bi[cyclopentane]-2-one;Δ1,1'-Bicyclopentane-2-one;2-Cyclopentylidenecyclopentanone,97%;BICYCLOPENTYLIDENE-2-ONE
• CAS NO: 825-25-2
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.22
• EINECS: 212-542-7
• Mol File: 825-25-2.mol
• Article Data: 45

Chemical Properties

• Melting Point: 74-75 °C
• Boiling Point: 231.78°C (rough estimate)
• Flash Point: 104°C
• Appearance: /
• Density: 1 g/cm3
• Vapor Pressure: 0.0142mmHg at 25°C
• Refractive Index: 1.5215 (estimate)
• CAS DataBase Reference: 2-CYCLOPENTYLIDENECYCLOPENTANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYCLOPENTYLIDENECYCLOPENTANONE(825-25-2)
• EPA Substance Registry System: 2-CYCLOPENTYLIDENECYCLOPENTANONE(825-25-2)

Safety Data

• Hazardous Substances Data: 825-25-2(Hazardous Substances Data)

Usage

Uses

Bicyclopentylidene-2-one is derived from Cyclopentanone (C988395), which is a chemical compound used in the synthesis of various simple and complex organic compounds. Also, it is used in the synthesis of peptidase IV inhibitors for the treatment of type 2 diabetes.

InChI:InChI=1/C10H14O/c11-10-7-3-6-9(10)8-4-1-2-5-8/h1-7H2

Upstream product

• 110-89-4 piperidine 
• 141-78-6 ethyl acetate 
• 120-92-3 cyclopentanone 
• 60-29-7 diethyl ether 
• 677-22-5 tert-butylmagnesium chloride 
• 141-52-6 sodium ethanolate 
• 75-20-7 calcium carbide 
• 124-41-4 sodium methylate 
• 67-64-1 acetone 
• 16424-32-1 2-Buthylidenecyclopentenone 
• 631-61-8 ammonium acetate 
• 1003-03-8 Cyclopentamine 
• 86119-84-8 phosphoric acid 
• 13388-94-8 spiro[4.5]decan-6-one 

Downstream Products

• 4884-25-7 2-cyclopentylcyclopentanol 
• 93651-35-5 2-benzylidene-5-cyclopentylidenecyclopentanone 
• 103225-42-9 1,1'-Difluoro-bicyclopentyl-2-one 
• 2866-71-9 (1,1'-bicyclopentyl)-2-one 
• 117712-77-3 (1'S,1''S)-[1,2';1',1'';2'',1''']Quatercyclopentane-1',1''-diol 
• 542-28-9 3,4,5,6-tetrahydro-2H-pyran-2-one 
• 104703-62-0 (E)-trisylhydrazone de la cyclopentylidene-2 cyclopentanone-1 
• 85554-06-9 2-cyclopent-1-enyl-2-<2-(phenylsulfinyl)-1-ethyl>cyclopentanone 
• 74542-37-3 1-<1-(5-Oxo-1-Cyclopentenyl)cyclopentyl>-4-phenyl-1,2,4-triazolidine-3,5-dione 
• 74542-36-2 1-<1-(1-Cyclopentenyl)-2-oxocyclopentyl>-4-phenyl-1,2,4-triazolidine-3,5-dione 
• 98470-84-9 1-Benzyl-2--cyclopenten-(1) 
• 934-02-1 bicyclopentyl-1,1'-diene 
• 97790-43-7 1-Phenyl-2--cyclopenten-(1) 
• 24071-97-4 5-Cyclopentyl-5-oxo-valeriansaeure-aethylester 

Relevant articles and documents

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Fine-Bubble-Slug-Flow Hydrogenation of Multiple Bonds and Phenols

We describe a promising method for the continuous hydrogenation of alkenes or alkynes by using a newly developed fine-bubble generator. The fine-bubble-containing slug-flow system was up to 1.4 times more efficient than a conventional slug-flow method. When applied in the hydrogenation of phenols to the corresponding cyclohexanones, the fine bubble-slug-flow method suppressed over-reduction. As this method does not require the use of excess gas, it is expected to be widely applicable in improving the efficiency of gas-mediated flow reactions.

Morphology-Tuned Activity of Ru/Nb2O5 Catalysts for Ketone Reductive Amination

Amines are important compounds in natural products and medicines. Specifically, cyclopentylamine is one of the value-added chemicals widely used in the production of pesticides, cosmetics and medicines. In this work, three Ru/Nb2O5 catalysts with different Nb2O5 morphologies were used in the reductive amination of cyclopentanone under mild reaction conditions (90 °C, 2 MPa H2), among which 1 %Ru/Nb2O5?L catalyst exhibits best performance with the yield of cyclopentylamine reaching 84 %. This catalytic system is stable and has not significant deactivation even after 5 runs in the durability test. In addition, this catalyst can be extended to a series of aldehydes/ketones. Further comprehensive characterizations (XPS analysis and CO-adsorption DRIFT) reveal that the electronic effect of Ru species can be ruled out; instead, the activity of the catalyst is strongly influenced by the geometric effect. Layered Nb2O5 material possesses the highest surface area, resulting in the highest Ru dispersion, and therefore shows the highest catalytic activity. The in-situ DRIFT-MS technique was also used to reveal and understand the reaction mechanism. It is found that Ru species play a key role in activating carbonyl groups. This study illustrates a promising application of Ru/Nb2O5-Layer catalyst in the synthesis of amine and provides an understanding to the reaction mechanism.