82898-92-8

Basic information

• Product Name: (2RS,4SR)-2,4-Dimethyl-N-<(R)-1-phenylethyl>glutarsaeure-monoamid
• CAS NO: 82898-92-8
• Molecular Weight: 263.337
• Mol File: 82898-92-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2RS,4SR)-2,4-Dimethyl-N-<(R)-1-phenylethyl>glutarsaeure-monoamid(CAS DataBase Reference)
• NIST Chemistry Reference: (2RS,4SR)-2,4-Dimethyl-N-<(R)-1-phenylethyl>glutarsaeure-monoamid(82898-92-8)
• EPA Substance Registry System: (2RS,4SR)-2,4-Dimethyl-N-<(R)-1-phenylethyl>glutarsaeure-monoamid(82898-92-8)

Safety Data

• Hazardous Substances Data: 82898-92-8(Hazardous Substances Data)

Upstream product

• 4295-92-5 (3R,5S)-3,5-dimethyldihydro-2H-pyran-2,6(3H)-dione 
• 3886-69-9 (R)-1-phenyl-ethyl-amine 

Downstream Products

• 74034-73-4 (3R,5S)-3,5-dimethyltetrahydro-2H-pyran-2-one 
• 82898-93-9 (2R,4S)-5-Hydroxy-2,4-dimethyl-N-<(R)-1-phenylethyl>pentanamid 
• 82917-22-4 (2S,4R)-5-Hydroxy-2,4-dimethyl-N-<(R)-1-phenylethyl>pentanamid 

Relevant articles and documents

Stereoselective Synthesis of Alcohols, XI. Double Stereodifferentiation in the Addition of Crotylboronates to Aldehydes: Prelog-Djerassi Lactone

Addition of the (Z)-crotylboronate 11 to (S)-(+)-α-methylbutyraldehyde (4) resulted in the Cram and Anti-Cram diastereomers 6 and 7.Their ratio depended on the chirality of the boronate component.Hence the formation of the alcohol 7 could be favoured by double stereodifferentiation.Similarly, on addition of the (E)-crotylboronate 12 predominant formation of the isomer 13 could be achieved.These observations formed the basis for a stereoselective synthesis of the Prelog-Djerassi lactone 3.